{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:39:17Z","timestamp":1777581557058,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,2,25]],"date-time":"2021-02-25T00:00:00Z","timestamp":1614211200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>Ocular features of Alport syndrome include anterior lenticonus, posterior polymorphous corneal dystrophy, and fleck-and-dot retinopathy in most cases. Keratoconus in such patients has been rarely mentioned in previous studies. To our knowledge, this is the first report of corneal cross-linking for halting the progression of keratoconus in a patient with Alport syndrome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case report:<\/jats:title>\n                    <jats:p>A 22-year-old male was referred for his initial corneal topography, after he was already prescribed with rigid gas-permeable contact lenses. Alport syndrome was diagnosed in his infancy and gene COL4A5 mutation was confirmed. Ophthalmological evaluation confirmed keratoconus. One-year follow-up showed a progression on his right eye and standard corneal cross-linking was performed. Stabilization of the disease marked by normalization in visual function and corneal tomography values was noticed 1\u2009year after the procedure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>When diagnosing ocular clinical findings of Alport syndrome, keratoconus should be considered. Standard corneal cross-linking protocol can halt its progression.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1120672121997672","type":"journal-article","created":{"date-parts":[[2021,2,26]],"date-time":"2021-02-26T02:09:54Z","timestamp":1614305394000},"page":"1584-1587","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Corneal cross-linking for treatment of progressive keratoconus in a patient with Alport syndrome: A case report"],"prefix":"10.1177","volume":"31","author":[{"given":"Iva","family":"Krolo","sequence":"first","affiliation":[{"name":"University Department of Ophthalmology, University Hospital Center Sestre milosrdnice, Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0948-6513","authenticated-orcid":false,"given":"Aida","family":"Kasumovi\u0107","sequence":"additional","affiliation":[{"name":"University Department of Ophthalmology, University Hospital Center Sestre milosrdnice, Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivana","family":"Radman","sequence":"additional","affiliation":[{"name":"University Department of Ophthalmology, University Hospital Center Sestre milosrdnice, Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pavao","family":"Pavi\u0107","sequence":"additional","affiliation":[{"name":"School of Medicine, University of Zagreb, Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,2,25]]},"reference":[{"key":"bibr1-1120672121997672","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.3454.504"},{"key":"bibr2-1120672121997672","doi-asserted-by":"publisher","DOI":"10.3109\/13816819709041431"},{"key":"bibr3-1120672121997672","doi-asserted-by":"publisher","DOI":"10.1186\/s40662-016-0047-5"},{"key":"bibr4-1120672121997672","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2011.237"},{"key":"bibr5-1120672121997672","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000000408"},{"key":"bibr6-1120672121997672","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/8.8.690"},{"key":"bibr7-1120672121997672","doi-asserted-by":"crossref","unstructured":"Miner JH, Baigent C, Flinter F, et al. The 2014 international workshop on Alport syndrome. Kidney Int 2014; 86(4): 679\u2013684.","DOI":"10.1038\/ki.2014.229"},{"key":"bibr8-1120672121997672","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-04393-2"},{"key":"bibr9-1120672121997672","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.10581014"},{"key":"bibr10-1120672121997672","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v7.i19.3012"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1120672121997672","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1120672121997672","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1120672121997672","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:45:54Z","timestamp":1777405554000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1120672121997672"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,25]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1177\/1120672121997672"],"URL":"https:\/\/doi.org\/10.1177\/1120672121997672","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,25]]}}}