{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:42:08Z","timestamp":1777581728624,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T00:00:00Z","timestamp":1649030400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To report the management of a case of candida endophthalmitis following intubation for SARS-CoV-2 ARDS, during the first lockdown, underlining consequently the limited access to the gold standard of care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Case report.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We have described the case of a 56-year-old Hispanic man who developed bilateral Candida endophthalmitis after one month of hospitalization in the intensive care unit for severe SARS-CoV-2 pneumonia. Multimodal imaging was obtained. Full serological screening for infection was done resulting negative. A diagnostic vitrectomy was impossible due to the limited access at the surgery room. Diagnosis of presumed candida endophthalmitis was made, according to a highly qualified center, and therapy with intravenous liposomal amphotericin B was administered. At three months, we observed lack of vitreous opacities and atrophic scars with no active lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Diagnosis of candida endophthalmitis was a challenge in this pandemic scenario, given the impossibility of performing a diagnostic vitrectomy. Therefore, it was mainly based on patient's clinical manifestations, multimodal imaging and on unanimity of collegiality between our hospital and the highly specialized center.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721221092190","type":"journal-article","created":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T04:24:59Z","timestamp":1649046299000},"page":"NP136-NP140","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Management of presumed candida endophthalmitis during the COVID-19 pandemic: Case report and review of the literature"],"prefix":"10.1177","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5798-1899","authenticated-orcid":false,"given":"Federica","family":"Fossataro","sequence":"first","affiliation":[{"name":"The Eye clinic, Melegnano Hospital, Milan, Italy"},{"name":"Department of Neurosciences, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Martines","sequence":"additional","affiliation":[{"name":"The Eye clinic, Melegnano Hospital, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7673-4276","authenticated-orcid":false,"given":"Piergiorgio","family":"Neri","sequence":"additional","affiliation":[{"name":"The Eye Institute, Uveitis service, Cleveland Clinic Abu Dhabi, United Arab Emirates"},{"name":"Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pia","family":"Allegri","sequence":"additional","affiliation":[{"name":"Ocular Inflammatory Diseases Regional Referral Center, Rapallo Hospital, Genova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo","family":"Pece","sequence":"additional","affiliation":[{"name":"The Eye clinic, Melegnano Hospital, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,4,4]]},"reference":[{"key":"bibr1-11206721221092190","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2001017"},{"key":"bibr2-11206721221092190","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2012-7"},{"key":"bibr3-11206721221092190","first-page":"14","volume":"18","author":"Opoka-Winiarska V","journal-title":"BMC Med"},{"key":"bibr4-11206721221092190","doi-asserted-by":"publisher","DOI":"10.1016\/j.mycmed.2020.100971"},{"key":"bibr5-11206721221092190","first-page":"509","volume":"140","author":"Jabs DA","journal-title":"Am J Ophthalmol"},{"key":"bibr6-11206721221092190","doi-asserted-by":"publisher","DOI":"10.3390\/jof6040211"},{"key":"bibr7-11206721221092190","doi-asserted-by":"publisher","DOI":"10.1080\/09273948.2021.1945111"},{"key":"bibr8-11206721221092190","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2020.102564"},{"key":"bibr9-11206721221092190","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197401000-00002"},{"key":"bibr10-11206721221092190","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000001630"},{"key":"bibr11-11206721221092190","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2007.133405"},{"key":"bibr12-11206721221092190","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ933"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11206721221092190","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/11206721221092190","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11206721221092190","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:46:23Z","timestamp":1777405583000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1177\/11206721221092190"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,4]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["10.1177\/11206721221092190"],"URL":"https:\/\/doi.org\/10.1177\/11206721221092190","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,4]]}}}