{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:42:14Z","timestamp":1777581734741,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2022,4,13]],"date-time":"2022-04-13T00:00:00Z","timestamp":1649808000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To describe the anatomic and visual outcomes of eyes undergoing autologous iris transplantation for macular hole retinal detachment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Seven consecutive patients with macular hole retinal detachment were enrolled in a single-arm prospective study. All patients underwent pars plana vitrectomy with autologous iris transplantation placed in the subretinal space as a plug to close the macular hole; in one case, a posterior retinal break was also closed with the same technique.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Seven patients (2 males and 5 females) with a mean age of 69.14\u2009\u00b1\u20097.79 years (range 58\u201380 years) were followed up for a period of six months. The best-corrected visual acuity improved from 2.44\u2009\u00b1\u20090.48 logMAR (20\/2000) preoperatively to 1.90\u2009\u00b1\u20090.26 logMAR (20\/800) 6 months after surgery. Optical coherence tomography analysis showed retinal adhesion around the iris plug, and the retina remained dry in the follow-up period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this series of macular hole retinal detachments, autologous iris transplantation placed as a plug over the retinal pigment epithelium facing the macular hole opening or directly over the bare sclera achieved anatomical success with improvement in visual function.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721221093196","type":"journal-article","created":{"date-parts":[[2022,4,13]],"date-time":"2022-04-13T13:34:48Z","timestamp":1649856888000},"page":"3720-3727","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Autologous Iris transplant as plug for macular hole retinal detachment in highly myopic eyes"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5560-4272","authenticated-orcid":false,"given":"Ciro","family":"Tamburrelli","sequence":"first","affiliation":[{"name":"Department of Ophthalmology and Ophthalmic network, Ospedale Oftalmico AUSLRoma1, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Rispoli","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Ophthalmic network, Ospedale Oftalmico AUSLRoma1, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Gentile","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Ophthalmic network, Ospedale Oftalmico AUSLRoma1, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna Clara","family":"Tamburrelli","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology La Sapienza University of 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