{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:32:19Z","timestamp":1777581139735,"version":"3.51.4"},"reference-count":47,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2022,6,29]],"date-time":"2022-06-29T00:00:00Z","timestamp":1656460800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the long-term outcomes of glaucoma management in patients with congenital ectropion uveae (CEU) over a period of three decades at a single large referral tertiary eye care center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective chart review of all patients with CEU treated surgically from 1990 to 2019 was performed. Primary combined trabeculotomy-trabeculectomy (CTT), trabeculectomy with and without mitomycin-C (MMC) (0.2\u2005mg\/mL for 1\u2005min) and transscleral cyclophotocoagulation (TSCPC) were performed. Intraocular pressure (IOP) \u22656 and \u226416\u2005mmHg without medications was considered as complete success and IOP\u2264 16\u2005mmHg with the use of upto 2 medications as qualified success.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 26 eyes of 21 patients were identified with a median age of 7 years (range, 6 days to 19 years) at the time of glaucoma surgery. Median follow-up was 51.1 months (range, 7\u2013244.6 months). Primary CTT was performed in 17 eyes (65%), trabeculectomy in 5 eyes (19%) with application of MMC in 2 eyes, and 3 eyes (12%) underwent TSCPC. One painful blind eye (4%) underwent evisceration. Mean IOP reduced from 30.8\u2009\u00b1\u20097.6\u2005mmHg on a mean of 1.3\u2009\u00b1\u20090.8 glaucoma medications preoperatively to a mean IOP of 15.2\u2009\u00b1\u20095.9\u2005mmHg (P\u2009&lt;\u20090.0001) on a mean of 0.2\u2009\u00b1\u20090.5 medications postoperatively at final follow-up (P\u2009=\u20090.0009). Complete success was achieved in 20 eyes, and qualified success in 2 eyes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>CTT is a safe and efficacious primary procedure for management of early-onset glaucoma in CEU. Trabeculectomy with or without adjuvant MMC is a viable second line of treatment in late-onset glaucoma with CEU for IOP control.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721221111595","type":"journal-article","created":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T02:19:04Z","timestamp":1656555544000},"page":"324-332","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Glaucoma management in congenital ectropion uveae: Surgical outcomes from a large tertiary referral center in South India"],"prefix":"10.1177","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6436-4060","authenticated-orcid":false,"given":"Anil K","family":"Mandal","sequence":"first","affiliation":[{"name":"Jasti V Ramanamma Children\u2019s Eye Care Centre, Child Sight Institute, Hyderabad, Telangana, India"},{"name":"VST Centre for Glaucoma Care, Hyderabad, Telangana, 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