{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:33:19Z","timestamp":1777581199204,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To evaluate corneal morphology after use of 0.5% intracameral moxifloxacin (ICM) in cataract surgery in patients who presented late with hard cataracts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Cross-sectional study conducted from June-2021 to December-2021 at a tertiary eye-care center. 90 patients over 60 years with high-risk characteristics for Covid-19, who presented late with higher grades of nuclear-sclerosis (NS), were included. They underwent phacoemulsification and 0.5%moxifloxacin (0.1\u2005ml) was injected intracamerally at the end of surgery. Best-corrected visual acuity (BCVA), intraocular pressures (IOP), endothelial cell density (ECD), coefficient of variation in cell-area (CoV), hexagonality (Hex) and central corneal thickness (CCT) were measured preoperatively and postoperatively on day1, day7 and day30. Statistical analysis was done by Anova test. p-value&lt;0.05 was considered significant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean age of presentation was 65.26\u00b18.3 years. Mean preoperative BCVA (1\/60-to-6\/60), IOP (16.7\u00b12.3\u2005mm of Hg), CCT (523.93\u00b139.6\u00b5), ECD (2547\u00b1302.08cells\/mm\n                      <jats:sup>2<\/jats:sup>\n                      ), Hex (47.04\u00b15.7%) and CoV (37.57\u00b13.9) changed to BCVA (6\/9-to-6\/6), IOP (17.5\u00b12.1\u2005mm of Hg), CCT (538.42\u00b136.9\u00b5), ECD (2388.40\u00b1339.25cells\/mm\n                      <jats:sup>2<\/jats:sup>\n                      ), Hex (44.44\u00b15.6%) and CoV (39.09\u00b14.5) at day30 postoperative. Average rate of change at day30 was increase in CCT (2.89%), ECD loss (6.4%), decrease in Hex (4.9%) and increase in CoV (4.6%), though clinically insignificant. No case of endophthalmitis or toxic-anterior segment syndrome seen.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>0.5% moxifloxacin (0.1\u2005ml) is safe as intracameral antibiotic to prevent postoperative infection in high-risk patients. The reported changes in the corneal parameters were within the range of any routine surgeries of hard senile cataracts. No specific effect could be attributed to ICM.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721221124673","type":"journal-article","created":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T02:24:18Z","timestamp":1662085458000},"page":"919-926","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact on corneal morphology after cataract surgery with intracameral moxifloxacin in neglected hard cataracts"],"prefix":"10.1177","volume":"33","author":[{"given":"Simple","family":"Gupta","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Command Hospital, Pune, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nitin","family":"Vichare","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Command Hospital, Pune, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Praveen","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Armed Forces Medical College, Pune, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4510-0668","authenticated-orcid":false,"given":"Mohini","family":"Agrawal","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Command Hospital, Pune, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anushree","family":"C.M.","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Armed Forces Medical College, Pune, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manish","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Critical Care, and Respiratory Medicine, AICTS, Pune, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,9,1]]},"reference":[{"key":"bibr1-11206721221124673","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12684"},{"key":"bibr2-11206721221124673","first-page":"1706","author":"Bratzler DW","year":"2004","journal-title":"Clinical Infectious Diseases"},{"key":"bibr3-11206721221124673","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2019.04.018"},{"key":"bibr4-11206721221124673","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(00)00124-X"},{"key":"bibr5-11206721221124673","doi-asserted-by":"publisher","DOI":"10.3341\/kjo.2018.0043"},{"key":"bibr6-11206721221124673","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(01)01306-2"},{"key":"bibr7-11206721221124673","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(02)01334-X"},{"key":"bibr8-11206721221124673","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(01)01270-6"},{"key":"bibr9-11206721221124673","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2007.10.041"},{"key":"bibr10-11206721221124673","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2020.102139"},{"key":"bibr11-11206721221124673","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2007.02.032"},{"key":"bibr12-11206721221124673","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2006.02.021"},{"key":"bibr13-11206721221124673","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2006.01.065"},{"key":"bibr14-11206721221124673","doi-asserted-by":"publisher","DOI":"10.29333\/ejgm\/82470"},{"key":"bibr15-11206721221124673","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2009.171009"},{"key":"bibr16-11206721221124673","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2005.04.015"},{"key":"bibr17-11206721221124673","doi-asserted-by":"publisher","DOI":"10.3109\/02713683.2012.763101"},{"key":"bibr18-11206721221124673","doi-asserted-by":"publisher","DOI":"10.7869\/djo.218"},{"key":"bibr19-11206721221124673","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2006.09.019"},{"key":"bibr20-11206721221124673","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2008.01771.x"},{"key":"bibr21-11206721221124673","doi-asserted-by":"publisher","DOI":"10.1007\/s00347-009-2027-9"},{"key":"bibr22-11206721221124673","first-page":"9","volume":"4","year":"2003","journal-title":"Negah Ophthalmol J"},{"key":"bibr23-11206721221124673","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2006.10.044"},{"issue":"5","key":"bibr24-11206721221124673","first-page":"822","volume":"7","author":"Ata\u015f M","year":"2014","journal-title":"International journal of ophthalmology"},{"key":"bibr25-11206721221124673","doi-asserted-by":"publisher","DOI":"10.21608\/ejhm.2019.44895"},{"issue":"6","key":"bibr26-11206721221124673","first-page":"14","volume":"9","author":"Amer SA","year":"2013","journal-title":"Journal of American Science"},{"key":"bibr27-11206721221124673","doi-asserted-by":"publisher","DOI":"10.4103\/2090-0686.168682"},{"key":"bibr28-11206721221124673","doi-asserted-by":"publisher","DOI":"10.1097\/j.jcrs.0000000000000064"},{"key":"bibr29-11206721221124673","unstructured":"United States Food and Drug Administration. FDA alerts health care professionals of risks associated with intraocular use of compounded moxifloxacin in drug safety and availability, August 2020, https:\/\/www.fda.gov\/drugs\/drug-safety-and-availability\/fda-alerts-health-care-professionals-risks-associated-intraocular-use-compounded-moxifloxacin."}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11206721221124673","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/11206721221124673","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11206721221124673","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:44:15Z","timestamp":1777405455000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/11206721221124673"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,1]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["10.1177\/11206721221124673"],"URL":"https:\/\/doi.org\/10.1177\/11206721221124673","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,1]]}}}