{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:34:12Z","timestamp":1777581252037,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T00:00:00Z","timestamp":1668384000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"publisher","award":["R01EY027301"],"award-info":[{"award-number":["R01EY027301"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Vitreous cortex hyalocytes (VCH) are resident macrophage cells that provide immunosurveillance, respond to tissue injury and inflammation, and help maintain the transparency of the media. In this case report we demonstrate the use of en face optical coherence tomography (OCT) to image VCH in vivo in a patient presenting with PAMM secondary to antiphospholipid syndrome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case description<\/jats:title>\n                    <jats:p>A 38-year-old female with no known medical history presented with complaints of visual disturbances in the right eye. OCT revealed hyperreflective bands in the IPL and INL nasal to the fovea. A diagnosis of PAMM was made. Work-up revealed elevated titers of antiphospholipid antibodies. En face OCT revealed a decline in the inflammatory activation over a seven-month period as evidenced by changes in VCH distribution and morphology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our findings suggest that monitoring changes in the distribution and morphology of VCH could have a potential clinical utility for assessing disease severity, predicting recovery, and early recognition of treatment response in various inflammatory ocular pathologies such as PAMM.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721221138303","type":"journal-article","created":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T02:02:32Z","timestamp":1668477752000},"page":"NP118-NP121","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Imaging vitreous cortex hyalocyte response to paracentral acute middle maculopathy (PAMM) using\n                    <i>En Face<\/i>\n                    OCT"],"prefix":"10.1177","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1591-9952","authenticated-orcid":false,"given":"Oscar","family":"Otero-Marquez","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sofia","family":"Ahsanuddin","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA"},{"name":"Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York City, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lily","family":"Spellman","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA"},{"name":"School of Medicine, New York Medical College, Valhalla, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Pinhas","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toco YP","family":"Chui","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA"},{"name":"Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York City, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard B","family":"Rosen","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA"},{"name":"Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York City, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,11,14]]},"reference":[{"key":"bibr1-11206721221138303","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2013.4056"},{"key":"bibr2-11206721221138303","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-020-04826-1"},{"key":"bibr3-11206721221138303","first-page":"1","volume":"61","author":"Castanos M V","year":"2020","journal-title":"Investig Ophthalmol Vis Sci"},{"key":"bibr4-11206721221138303","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.449417"},{"key":"bibr5-11206721221138303","first-page":"1","volume":"2022","author":"Otero-Marquez O","year":"2022","journal-title":"Case Rep Ophthalmol 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