{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T11:39:36Z","timestamp":1788435576189,"version":"build-2803163510"},"reference-count":28,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2023,4,19]],"date-time":"2023-04-19T00:00:00Z","timestamp":1681862400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81770955"],"award-info":[{"award-number":["81770955"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>\n                      To investigate the long-term clinical outcomes and changes in crystalline lens transparency after accelerated (45 mW\/cm\n                      <jats:sup>2<\/jats:sup>\n                      ) transepithelial corneal cross-linking (ATE-CXL) using the Pentacam imaging system in patients with progressive keratoconus.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The study prospectively included 44 keratoconus eyes of 40 patients (mean age: 24.39\u2009\u2009\u00b1\u2009\u20095.61 years) who underwent ATE-CXL. The examinations, including assessment of uncorrected distance visual acuity, corrected distance visual acuity, corneal topography, and corneal endothelial cell density count, were conducted preoperatively and 1 month, 3 months, 6 months, 1 year, and 5 years postoperatively. Measurement of crystalline lens density using Pentacam images was also performed pre- and postoperatively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All surgeries were uneventful with no postoperative complications. All keratometry values and corneal thickness remained stable during the 5-year follow-up period (all p\u2009&gt;\u20090.05). There were no significant differences in corneal endothelial cell density count, visual acuity, and anterior average lens density in the 0.5-, 1.0-, and 1.5-mm depth zones during the 5-year follow-up period compared with the preoperative values (all p\u2009&gt;\u20090.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      The results of this study suggest that ATE-CXL at 45 mW\/cm\n                      <jats:sup>2<\/jats:sup>\n                      is safe and effective for the treatment of progressive keratoconus in terms of both crystalline lens density and endothelial cell density.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721231170036","type":"journal-article","created":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T03:58:46Z","timestamp":1681963126000},"page":"1850-1859","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Long-term changes in crystalline lens transparency after accelerated transepithelial corneal cross-linking in patients with keratoconus"],"prefix":"10.1177","volume":"33","author":[{"given":"Ling","family":"Sun","sequence":"first","affiliation":[{"name":"Key NHC Key Laboratory of Myopia (Fudan University); 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