{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T02:20:04Z","timestamp":1782440404911,"version":"3.54.5"},"reference-count":17,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2023,7,27]],"date-time":"2023-07-27T00:00:00Z","timestamp":1690416000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate and compare the pain experience and discomfort during cataract surgery and over the 24\u2005hours after surgery in patients undergoing either topical anesthesia alone or topical anesthesia plus intracameral anesthesia, provided by using a standard topical anesthesia regimen and a 0.2-mL dose of Mydrane\u00ae.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Prospective study involving 100 patients who underwent cataract surgery receiving either topical anesthesia alone (group 1, n\u2009=\u200950) or topical anesthesia plus intracameral anesthesia (group 2, n\u2009=\u200950) between January 2021 and March 2022. The pain experienced by patients during and after surgery was assessed using a pain scale and a questionnaire. One hour after surgery, patients were asked to rate the intensity of discomfort they experienced throughout the procedure by pointing to a 0\u2013100 Visual Analogue Scale (VAS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>According to VAS measurements, patients who underwent surgery under topical anesthesia reported more significant pain than those who underwent surgery under topical anesthesia plus intracameral anesthesia during and over the 24\u2005hours after surgery. ( p\u2009=\u20090.02 and p\u2009=\u20090.01, respectively). Patients undergoing topical anesthesia had 2.34-fold greater odds of having pain during surgery [95% Confidence Interval (CI): 1.58\u20135.25, p\u2009=\u20090.03].<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Topical anesthesia plus intracameral anesthesia lower intraoperative and postoperative pain levels, improving patient cooperation and representing a useful analgesic delivery method in cataract surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721231187424","type":"journal-article","created":{"date-parts":[[2023,7,27]],"date-time":"2023-07-27T13:53:57Z","timestamp":1690466037000},"page":"425-431","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Pain experience in patients undergoing topical anesthesia alone versus topical plus intracameral anesthesia during cataract surgery"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7968-1336","authenticated-orcid":false,"given":"Matteo","family":"Ripa","sequence":"first","affiliation":[{"name":"Ophthalmology Unit, \u201cFondazione Policlinico Universitario A. Gemelli IRCCS\u201d, Rome, Italy"},{"name":"Ophthalmology Department, Catholic University \u201cSacro Cuore\u201d, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Ricci","sequence":"additional","affiliation":[{"name":"Ophthalmology Unit, \u201cFondazione Policlinico Universitario A. Gemelli IRCCS\u201d, Rome, Italy"},{"name":"Ophthalmology Department, Catholic University \u201cSacro Cuore\u201d, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanislao","family":"Rizzo","sequence":"additional","affiliation":[{"name":"Ophthalmology Unit, \u201cFondazione Policlinico Universitario A. Gemelli IRCCS\u201d, Rome, Italy"},{"name":"Ophthalmology Department, Catholic University \u201cSacro Cuore\u201d, Rome, Italy"},{"name":"Consiglio Nazionale delle Ricerche, Istituto di Neuroscienze, Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,7,27]]},"reference":[{"key":"bibr1-11206721231187424","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)30544-5"},{"key":"bibr2-11206721231187424","unstructured":"Future of cataract surgery seems promising, https:\/\/www.healio.com\/news\/ophthalmology\/20210126\/future-of-cataract-surgery-seems-promising (accessed 7 December 2022)."},{"key":"bibr3-11206721231187424","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.13.6.691"},{"key":"bibr4-11206721231187424","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2017.08.020"},{"key":"bibr5-11206721231187424","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(97)80211-8"},{"key":"bibr6-11206721231187424","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/383456"},{"key":"bibr7-11206721231187424","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2010.188003"},{"key":"bibr8-11206721231187424","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2007.09.021"},{"key":"bibr9-11206721231187424","doi-asserted-by":"publisher","DOI":"10.1076\/opep.9.2.83.1523"},{"key":"bibr10-11206721231187424","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(97)30128-6"},{"key":"bibr11-11206721231187424","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(85)33820-4"},{"key":"bibr12-11206721231187424","doi-asserted-by":"publisher","DOI":"10.1177\/11206721221146676"},{"key":"bibr13-11206721231187424","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfo.2019.02.015"},{"key":"bibr14-11206721231187424","doi-asserted-by":"publisher","DOI":"10.1097\/j.jcrs.0000000000000491"},{"key":"bibr15-11206721231187424","volume":"7","author":"Minakaran N","year":"2020","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr16-11206721231187424","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2020.00440"},{"key":"bibr17-11206721231187424","doi-asserted-by":"publisher","DOI":"10.1007\/s40123-020-00311-4"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11206721231187424","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/11206721231187424","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11206721231187424","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:45:19Z","timestamp":1777405519000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1177\/11206721231187424"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,27]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["10.1177\/11206721231187424"],"URL":"https:\/\/doi.org\/10.1177\/11206721231187424","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,27]]}}}