{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:18:25Z","timestamp":1787235505364,"version":"build-2736575974"},"reference-count":34,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate choroidal findings on multimodal imaging in eyes within pachychoroid spectrum diseases and to compare quantitative and qualitative choroidal features between non-neovascular (NNV-PDS) and neovascular (NV-PDS) pachychoroid diseases<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective cross-sectional study comparing between NV-PDS and NNV-PDS. All patients underwent multimodal imaging including infracyanine green angiography (IFCGA) and swept source optical coherence tomography (OCT) and angiography (OCT-A). The following parameters were analyzed: subfoveal choroidal thickness (SFCT), choroidal vascular index (CVI), presence of pachyvessels and choroidal vascular interconnections (CVIC), presence of choroidal neovascularization and choriocapillaris density.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 87 eyes included in the study, 63 eyes (73%) had NNV-PDS and 24 eyes (27%) had NV-PDS. Mean SFCT and CVI were significantly higher in NNV-PDS group (p\u2009=\u20090.01; p\u2009=\u20090.022). Pachyvessels were more diffusely distributed in NNV-PD group and more focally distributed in NV-PDS group (p\u2009=\u20090.029). CVIC were more frequently noted in NV-PDS group (p\u2009=\u20090.024). A higher CVI was associated to a thicker choroid (p\u2009&lt;\u20090.001), with significant negative correlations between the presence of CVIC and both SFCT (p\u2009=\u20090.015) and CVI (p\u2009=\u20090.002). We also observed a lower choriocapillaris vascular density and higher number of choriocapillaris flow voids in eyes with NNV-PDS (p\u2009=\u20090.24; p\u2009=\u20090.61).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>NNV-PDS eyes had a significantly thicker SFCT, higher CVI and a lower rate of detected CVIC than eyes with NV-PDS. These highlighted choroidal vascular changes might lead to a better understanding of pachychoroid disease pathophysiology. More frequently observed in NV-PDS group, CVIC are believed to assess the development of vortex vein anastomoses as a remodelling process for vascular decongestion.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721231210755","type":"journal-article","created":{"date-parts":[[2023,11,2]],"date-time":"2023-11-02T01:00:27Z","timestamp":1698886827000},"page":"1191-1200","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Choroidal features in non-neovascular and neovascular pachychoroid diseases"],"prefix":"10.1177","volume":"34","author":[{"given":"Ines","family":"Hachicha","sequence":"first","affiliation":[{"name":"Department of ophthalmology B, Institut H\u00e9di Raies d\u2019ophtalmologie de Tunis, Tunis, Tunisia"},{"name":"Facult\u00e9 de m\u00e9decine de Tunis, Universit\u00e9 Tunis - El Manar, Tunis, 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