{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:37:53Z","timestamp":1777581473819,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T00:00:00Z","timestamp":1698710400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>We describe a report of three cases of bilateral Peripapillary Hyperreflective Ovoid Mass-Like Structures (PHOMS), their respective multimodal imaging, and retinal nerve fiber layer (RNFL) analysis over time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed an elaborated multimodal imaging of three pediatric patients with PHOMS. We performed a visual acuity testing, followed by a biomicroscopic and fundus examination, an additional Optical Coherence Tomography (OCT), fundus autofluorescence (FAF), infra-red (IR), fluorescein angiography (FA), Scanning laser Ophtalmoscopy (SLO), and retro-mode imaging. Furthermore, we analyzed RNFL thickness over several consecutive visits.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The multimodal approach exhibited similar characteristics of PHOMS in all eyes, namely a torus-like shaped that was particularly demarcated and well visualized using SLO and retro-mode tool. In all the eyes, we found a downward trend of the RNFL over time. In both the right and left eye, RNFL at presentation averaged at 152.33\u2009\u00b1\u200925.42 and 130\u2009\u00b1\u200918.33 microns, respectively. Several weeks after, it averaged at 142\u2009\u00b1\u200930.34 and 125.67\u2009\u00b1\u200914.84 microns, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our report shows a thinning trend of the RNFL thickness over time in patients with PHOMS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721231211419","type":"journal-article","created":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T03:12:15Z","timestamp":1698721935000},"page":"NP126-NP130","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Peripapillary hyperreflective ovoid mass-like structures and the retinal nerve fiber layer thinning"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4856-5567","authenticated-orcid":false,"given":"Mark","family":"Rabinovich","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, University of Paris Est-Cr\u00e9teil, Cr\u00e9teil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samia","family":"Seray","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of Paris Est-Cr\u00e9teil, Cr\u00e9teil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Amoroso","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of Paris Est-Cr\u00e9teil, Cr\u00e9teil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Madar","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of Paris Est-Cr\u00e9teil, Cr\u00e9teil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric H","family":"Souied","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of Paris Est-Cr\u00e9teil, Cr\u00e9teil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,10,31]]},"reference":[{"key":"bibr1-11206721231211419","doi-asserted-by":"publisher","DOI":"10.1097\/WNO.0000000000000585"},{"key":"bibr2-11206721231211419","doi-asserted-by":"publisher","DOI":"10.1097\/WNO.0000000000001203"},{"key":"bibr3-11206721231211419","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2013.01.024"},{"key":"bibr4-11206721231211419","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-020-1067-x"},{"key":"bibr5-11206721231211419","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-020-0890-4"},{"key":"bibr6-11206721231211419","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.796667"},{"key":"bibr7-11206721231211419","doi-asserted-by":"publisher","DOI":"10.1111\/ceo.14182"},{"key":"bibr8-11206721231211419","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-1313.2012.00902.x"},{"key":"bibr9-11206721231211419","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11133715"},{"key":"bibr10-11206721231211419","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-019-0694-6"},{"key":"bibr11-11206721231211419","doi-asserted-by":"publisher","DOI":"10.1016\/j.sjopt.2014.02.003"},{"key":"bibr12-11206721231211419","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2020.01.014"},{"key":"bibr13-11206721231211419","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfo.2022.12.034"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11206721231211419","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/11206721231211419","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11206721231211419","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:45:42Z","timestamp":1777405542000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1177\/11206721231211419"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,31]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["10.1177\/11206721231211419"],"URL":"https:\/\/doi.org\/10.1177\/11206721231211419","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,31]]}}}