{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:38:05Z","timestamp":1777581485172,"version":"3.51.4"},"reference-count":55,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2023,11,5]],"date-time":"2023-11-05T00:00:00Z","timestamp":1699142400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>To evaluate the correlations between anatomical and functional changes after idiopathic epiretinal membrane (iERM) surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this prospective, observational, single-center study, consecutive patients who underwent iERM peeling were enrolled. Reported data were pre- and postoperative best-corrected visual acuity (BCVA), retinal sensitivity (RS) and fixation stability values on microperimetry, structural macular features on SD-OCT and OCTA. RS of foveal and parafoveal area was analysed and two sub-groups were identified whether RS improved or remained unchanged\/worsened after surgery; consequently, vascular perfusion density (VPD) of the same area was studied.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty-nine eyes of 29 patients were examined. The post-operative improvement in terms of BCVA, RS and fixation within the central 4 degrees was significant (p\u2009&lt;\u20090.001, p\u2009&lt;\u20090.001, p\u2009=\u20090.001), as well as the foveal thickness and macular volume change\/reduction (p\u2009&lt;\u20090.001). The pre-operative superficial VPD, choriocapillaris VPD and capillary free zone (CFZ) area were significantly reduced compared to the fellow healthy eye (p\u2009=\u20090.001, p\u2009=\u20090.02, p\u2009&lt;\u20090.001). Choriocapillaris VPD showed a statistically significant increase after surgery (p\u2009&lt;\u20090.02). Superficial, deep and choriocapillaris VPD of the improved RS group showed a significant increase both in foveal (p\u2009=\u20090.03, p\u2009=\u20090.03, p\u2009=\u20090.01) and parafoveal areas (p\u2009=\u20090.01, p\u2009=\u20090.03, p\u2009=\u20090.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>We reported a higher VPD in the retinal area that experienced a retinal sensitivity improvement 6 months after ERM surgery. This result objectifies the tight bond between visual function and retinal perfusion in ERM patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721231212823","type":"journal-article","created":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T00:48:02Z","timestamp":1699231682000},"page":"1228-1238","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Correlation between retinal sensitivity and retinal vascular perfusion after idiopathic epiretinal membrane peeling"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8302-6107","authenticated-orcid":false,"given":"Michele","family":"Nicolai","sequence":"first","affiliation":[{"name":"Eye Clinic, Polytechnic University of Marche, via Conca 61, 60126, Ancona, Marche, 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