{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T21:33:41Z","timestamp":1778708021165,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T00:00:00Z","timestamp":1723593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2024,11]]},"abstract":"\n Introduction<\/jats:title>\n Neurofibromatosis type I, also known as Von Recklinghausen disease, is a common phakomatosis affecting 1 in 2500\u20133000 live births; it may be associated with several common ocular findings, including Lisch nodules, plexiform neurofibromas, optic pathway gliomas, retinal astrocytic hamartomas and choroidal nodules.<\/jats:p>\n <\/jats:sec>\n \n Case description<\/jats:title>\n This report illustrates clinical evidence of simultaneous presence of retinal reactive astrocytic tumor (RRAT) and two retinal astrocytic hamartomas (RAH) in a 15 y\/o patient with NF1, referred to our attention because of an asymptomatic fundus mass in his right eye of recent onset.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n This case, in addition to considering NF1 as one of the ocular conditions associated with secondary RRAT, underlines the importance of early referral and continuous ophthalmological follow-up in preventing possible complications that could cause significant visual impairment in patients with NF1.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/11206721241275143","type":"journal-article","created":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T10:39:08Z","timestamp":1723631948000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Retinal Reactive Astrocytic Tumor and Astrocytic hamartomas in patient with Neurofibromatosis type 1: Case Report and Literature review"],"prefix":"10.1177","volume":"34","author":[{"given":"Theodora","family":"Hadjistilianou","sequence":"first","affiliation":[{"name":"Department of Medicine, Surgery and Neuroscience, Unit of Ophthalmology, Ocular Oncology, University of Siena, Siena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4289-1723","authenticated-orcid":false,"given":"Alberto","family":"Carnicci","sequence":"additional","affiliation":[{"name":"Department of Medicine, Surgery and Neuroscience, Unit of Ophthalmology, Ocular Oncology, University of Siena, Siena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"D\u2019Alessandro","sequence":"additional","affiliation":[{"name":"Department of Medicine, Surgery and Neuroscience, Unit of Ophthalmology, Ocular Oncology, University of Siena, Siena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonia","family":"De Francesco","sequence":"additional","affiliation":[{"name":"Department of Medicine, Surgery and Neuroscience, Unit of Ophthalmology, Ocular Oncology, University of Siena, Siena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3869-8593","authenticated-orcid":false,"given":"Mario","family":"Fruschelli","sequence":"additional","affiliation":[{"name":"Department of Medicine, Surgery and Neuroscience, Unit of Ophthalmology, Ocular Oncology, University of Siena, Siena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,8,14]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2013.6281"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1991.01080050076033"},{"key":"e_1_3_2_4_2","unstructured":"Rowley SA O\u2019callaghan FJ Osborne JP. 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