{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:44:07Z","timestamp":1777581847775,"version":"3.51.4"},"reference-count":41,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T00:00:00Z","timestamp":1723593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Comparing the effect of standard trabeculectomy with direct sutures versus trabeculectomy with compression and everting sutures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Mono-centric randomized prospective comparative study on 38 glaucomatous eyes undergoing trabeculectomy: 19 with standard fixed sutures (group A) and 19 withremovable regulating sutures (group B). Preoperatively and at day-7, 1-month, 2-months, 3-months and 6-months after surgery, we recorded best-corrected visual acuity (BCVA), intraocular pressure (IOP) and possible complications. Complete, partial success and failure rates were recorded at the end of the study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In group B, we pulled everting sutures with the \u201chorse bridle\u201d technique at the 14\n                      <jats:sup>th<\/jats:sup>\n                      day, and successively removed all sutures between the 14\n                      <jats:sup>th<\/jats:sup>\n                      -30\n                      <jats:sup>th<\/jats:sup>\n                      post-operative day. At month-1, we recorded a significant IOP reduction in both groups (mean reduction of 11.5 mmHg for group A and of 14.4 mmHg for Group B, p\u2009=\u20090.001 and p\u2009&lt;\u20090.0001, respectively). Furthermore, group B showed a significantly lower IOP than group A (\u22124.2 mmHg, 95% confidence interval [CI] \u22127.0 to \u22120.5 mmHg for group B, p\u2009=\u20090.01). At 2, 3 and 6-months, no significant IOP differences were reported between the two groups (all p\u2009&gt;\u20090.05), but failure rate was higher for group A (21%) than for group B (11%). No differences in visual outcomes at any timepoints were noted.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Trabeculectomy with removable regulating sutures showed a good safety profile, comparable to standard trabeculectomy. Moreover, we reported a lower IOP one month postoperatively, suggesting this technique may optimize early management of trabeculectomy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721241276573","type":"journal-article","created":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T10:15:18Z","timestamp":1723630518000},"page":"961-971","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Removable regulating sutures during trabeculectomy for a safer and more effective intraocular pressure control"],"prefix":"10.1177","volume":"35","author":[{"given":"Alfonso","family":"Savastano","sequence":"first","affiliation":[{"name":"Ophthalmology Department, \u201cFondazione Policlinico Universitario A. 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