{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T11:22:40Z","timestamp":1778325760523,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2024,11,18]],"date-time":"2024-11-18T00:00:00Z","timestamp":1731888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>This study investigates the natural progression of quiescent macular neovascularization (qMNV) using optical coherence tomography angiography (OCTA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The study monitored 30 eyes of 28 qMNV patients over a period of at least six months. Best-corrected visual acuity (BCVA), optical coherence tomography (OCT), and OCTA were used to perform qualitative and quantitative analyses, noting any cases of activation during follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among the 30 eyes (14 female, mean age 69.70\u2009\u00b1\u20097.63 years), 21 had age-related macular degeneration (AMD) and 9 had pachychoroid neovasculopathy (PNV). The mean follow-up duration was 18.9 months. There were no significant changes in qualitative morphological features, BCVA, or choroidal thickness (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). However, there was a statistically significant increase in the areas of MNV and flow (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.043 and\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.018, respectively). BCVA and MNV area showed no significant correlation (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.103). Four cases (13.33%) showed activation after an average follow-up period of 27.75 months (6 to 48). Additionally, extrafoveal location was identified as a significant risk factor for exudation (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.033).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>OCTA is a valuable tool for monitoring qMNV and identifying potential predictors of disease activation. The qMNV area may increase over time, even in the absence of activation. Extrafoveal location appears to be a potential risk factor for qMNV activation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721241298025","type":"journal-article","created":{"date-parts":[[2024,11,18]],"date-time":"2024-11-18T05:43:17Z","timestamp":1731908597000},"page":"1075-1081","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Analysis of the Natural Course of Quiescent Macular Neovascularization with Optical Coherence Tomography Angiography"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1315-3690","authenticated-orcid":false,"given":"Yeliz","family":"Delibay Akgun","sequence":"first","affiliation":[{"name":"Ophthalmology Department, Bismil State Hospital, Diyarbak\u0131r, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emin","family":"Kurt","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Medical School, Celal Bayar University, Manisa, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0239-0180","authenticated-orcid":false,"given":"Muhammed","family":"Altinisik","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Medical School, Celal Bayar University, Manisa, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,11,18]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13071309"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(98)99030-3"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.13-11665"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/1120672120986370"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.oret.2018.02.002"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.oret.2017.01.003"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.3928\/23258160-20181203-02"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-020-0936-7"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.5301\/ejo.5000995"},{"key":"e_1_3_3_11_2","first-page":"205","article-title":"Serous retinal pigment epithelial detachment with a notch: a sign of occult choroidal neovascularization","volume":"23","author":"Gass JDM","year":"2003","unstructured":"Gass JDM. Serous retinal pigment epithelial detachment with a notch: a sign of occult choroidal neovascularization. Retina 2003; 23: 205\u2013220.","journal-title":"Retina"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-021-05127-x"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2017.07.009"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2022.101113"},{"key":"e_1_3_3_15_2","first-page":"692","article-title":"A comparison of subfoveal to parafoveal choroidal blood flow dynamics","volume":"56","author":"Lovasik JV","year":"2015","unstructured":"Lovasik JV, Kergoat H. A comparison of subfoveal to parafoveal choroidal blood flow dynamics. Invest Ophthalmol Vis Sci 2015; 56: 692.","journal-title":"Invest Ophthalmol Vis Sci"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11206721241298025","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/11206721241298025","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11206721241298025","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:47:00Z","timestamp":1777405620000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/11206721241298025"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,18]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1177\/11206721241298025"],"URL":"https:\/\/doi.org\/10.1177\/11206721241298025","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,18]]}}}