{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:46:00Z","timestamp":1777581960136,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,11,18]],"date-time":"2024-11-18T00:00:00Z","timestamp":1731888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:p>Purpose. To report a rare case of Rosai-Dorfman-Destombes (RDD) disease in a teenage girl exhibiting mild fever, night chills, vertigo, and progressive bilateral vision and hearing loss. Method. Case report of a 15-year-old girl who underwent extensive ophthalmic multimodal imaging and a comprehensive workup evaluation. Results. Multiple choroid lesion masses in both eyes associated with systemic multifocal lymphadenopathy, involvement of the paranasal sinuses, and unusual intracranial manifestations well-shown by magnetic resonance imaging (MRI) and whole-body PET-scan. The PET-Scan and MRI imaging showed dural-based intracranial lesions, choroid-plexus signaling, and meningeal spread, as well as a focus on the paranasal sinuses, which helped determine the best biopsy location for a definitive diagnosis through immunohistochemistry. Conclusions. Here we describe a rare condition of RDD disease with bilateral visual and hearing loss associated with bilateral multiple choroid masses and neurological symptoms in an adolescent female patient. A definitive diagnosis relied on histological assessment, emphasizing the importance of interdisciplinary evaluation. RDD should be considered in the differential diagnosis of choroidal metastasis, tuberculosis, and other lymphoproliferative diseases.<\/jats:p>","DOI":"10.1177\/11206721241300634","type":"journal-article","created":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T02:00:43Z","timestamp":1731981643000},"page":"NP22-NP27","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Rosai-Dorfman-Destombes disease in adolescence with hearing and vision loss involvement: A multidisciplinary approach"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1534-942X","authenticated-orcid":false,"given":"Marina Gaglianone Teodoro","family":"da Silva","sequence":"first","affiliation":[{"name":"Ophthalmology division, S\u00e3o Jos\u00e9 do Rio Preto Medical School (FAMERP), S\u00e3o Jos\u00e9 do Rio Preto, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Cunha de Souza","sequence":"additional","affiliation":[{"name":"Ophthalmology division, S\u00e3o Jos\u00e9 do Rio Preto Medical School (FAMERP), S\u00e3o Jos\u00e9 do Rio Preto, Brazil"},{"name":"Ophthalmology division, collaborating professor, University of S\u00e3o Paulo (USP), S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inara Figueiredo","family":"Jacobsen","sequence":"additional","affiliation":[{"name":"Ophthalmology division, S\u00e3o Jos\u00e9 do Rio Preto Medical School (FAMERP), S\u00e3o Jos\u00e9 do Rio Preto, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Nath\u00e1lia Vilela","family":"Assis","sequence":"additional","affiliation":[{"name":"Ophthalmology division, S\u00e3o Jos\u00e9 do Rio Preto Medical School (FAMERP), S\u00e3o Jos\u00e9 do Rio Preto, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Ant\u00f4nio Carlos Pond\u00e9","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Radiology division, S\u00e3o Jos\u00e9 do Rio Preto Medical School (FAMERP), S\u00e3o Jos\u00e9 do Rio Preto, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murilo Wendeborn","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Ophthalmology division, S\u00e3o Jos\u00e9 do Rio Preto Medical School (FAMERP), S\u00e3o Jos\u00e9 do Rio Preto, Brazil"},{"name":"Ophthalmology division, collaborating professor at the Ribeir\u00e3o Preto Medical School, University of S\u00e3o Paulo (USP), Ribeir\u00e3o Preto, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,11,18]]},"reference":[{"key":"bibr1-11206721241300634","first-page":"63","volume":"87","author":"Rosai J","year":"1969","journal-title":"Arch 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