{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:18:16Z","timestamp":1777580296549,"version":"3.51.4"},"reference-count":28,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2025,4,15]],"date-time":"2025-04-15T00:00:00Z","timestamp":1744675200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the causes of corneal epithelial defects (CEDs) due to mechanical trauma and analyze the risk factors for progression to persistent epithelial defects (PEDs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A retrospective analyze 241 patients (241 eyes) with CEDs caused by mechanical ocular trauma. All patients received initial treatment as outpatients at our hospital. Data collected included patients\u2019 basic information, injury causes, use of adjunctive treatments, improvement in symptoms and adverse reactions before and after treatment. Logistic regression analysis was used to explore the relationship between the causes of injury, the use of adjunctive treatments, and the occurrence of persistent corneal epithelial defects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The study involved 241 patients: 164 males (68.1%) and 77 females (31.9%), averaging 38.06\u2009\u00b1\u200917.88 years old. The most common age groups were 31\u201340 years (24.1%), 41\u201350 years (19.9%), and 51\u201360 years (18.2%). The top five causes of injury were finger pokes (20.4%), impacts from plastic objects (14.6%), branch strikes (13.3%), paper cuts (8.8%), and metal scratches (8.3%). 164 patients used recombinant human growth factor (rhEGF) eye drops with an average healing time of 3.2\u2009\u00b1\u20091.3 days, while 77 did not use these drops, averaging 7.4\u2009\u00b1\u20092.2 days. Continuous use of bandage lenses was a risk factor for persistent epithelial defects (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Treatment of CEDs caused by mechanical trauma should focus on managing ocular surface inflammation. The use of rhEGF eye drops can be an effective supplement treatment for CEDs. However, caution is needed regarding the use of bandage lenses.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721251333590","type":"journal-article","created":{"date-parts":[[2025,4,15]],"date-time":"2025-04-15T10:51:22Z","timestamp":1744714282000},"page":"1818-1823","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Trauma-induced corneal epithelial defects may lead to persistent epithelial defects exacerbated by prolonged use of bandage lenses"],"prefix":"10.1177","volume":"35","author":[{"given":"Donghai","family":"Wu","sequence":"first","affiliation":[{"name":"Xiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, Xiamen, China"},{"name":"Xiamen Clinical Research Center for Eye Diseases, Xiamen, Fujian, China"},{"name":"Xiamen Key Laboratory of Ophthalmology, Xiamen, Fujian, China"},{"name":"Fujian Key Laboratory of Corneal &amp; Ocular Surface Diseases, Xiamen, Fujian, China"},{"name":"Xiamen Key Laboratory of Corneal &amp; Ocular Surface Diseases, Xiamen, Fujian, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6576-4915","authenticated-orcid":false,"given":"Yuan","family":"Lin","sequence":"additional","affiliation":[{"name":"Xiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, Xiamen, China"},{"name":"Xiamen Clinical Research Center for Eye Diseases, Xiamen, Fujian, China"},{"name":"Xiamen Key Laboratory of Ophthalmology, Xiamen, Fujian, China"},{"name":"Fujian Key Laboratory of Corneal &amp; Ocular Surface Diseases, Xiamen, Fujian, China"},{"name":"Xiamen Key Laboratory of Corneal &amp; Ocular Surface Diseases, Xiamen, Fujian, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huping","family":"Wu","sequence":"additional","affiliation":[{"name":"Xiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, Xiamen, China"},{"name":"Xiamen Clinical Research Center for Eye Diseases, Xiamen, Fujian, China"},{"name":"Xiamen Key Laboratory of Ophthalmology, Xiamen, Fujian, China"},{"name":"Fujian Key Laboratory of Corneal &amp; Ocular Surface Diseases, Xiamen, Fujian, China"},{"name":"Xiamen Key Laboratory of Corneal &amp; Ocular Surface Diseases, Xiamen, Fujian, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinhong","family":"Cai","sequence":"additional","affiliation":[{"name":"Xiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, Xiamen, China"},{"name":"Xiamen Clinical Research Center for Eye Diseases, Xiamen, Fujian, China"},{"name":"Xiamen Key Laboratory of Ophthalmology, Xiamen, Fujian, China"},{"name":"Fujian Key Laboratory of Corneal &amp; Ocular Surface Diseases, Xiamen, Fujian, China"},{"name":"Xiamen Key Laboratory of Corneal &amp; Ocular Surface Diseases, Xiamen, Fujian, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,4,15]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2023.06.001"},{"key":"e_1_3_2_3_2","first-page":"123","article-title":"Management of corneal abrasions","volume":"70","author":"Wilson SA","year":"2004","unstructured":"Wilson SA, Last A. 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