{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:18:13Z","timestamp":1777580293287,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T00:00:00Z","timestamp":1745280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Amyloidosis, characterized by extracellular protein misfolding and deposition. Localized immunoglobulin light chain amyloidosis can present with atypical features.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>This case report elucidates an unconventional manifestation of localized immunoglobulin light chain amyloidosis characterized by recurrent and spontaneous eyelid ecchymosis alternating with episodes of incomplete resolution, a novelty in current literature, along with associated cutaneous changes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>This rare presentation underscores the importance of considering amyloidosis in the differential diagnosis of unusual periocular findings and may assist in identifying similar cases of atypical eyelid amyloidosis, especially in cases with limited involvement, promoting early diagnosis and intervention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721251333603","type":"journal-article","created":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T16:02:48Z","timestamp":1745337768000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Toward comprehending uncommon periocular manifestations: A case of localized AL amyloidosis with a rare spontaneous eyelid ecchymosis"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5607-6237","authenticated-orcid":false,"given":"Caio Brenno","family":"Abreu","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Hospital Universit\u00e1rio Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B\u00e1rbara Flores Culau","family":"Merlo","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Hospital Universit\u00e1rio Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rcio Penha Morter\u00e1","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Hospital Universit\u00e1rio Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda Galante","family":"Dourado","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Hospital Universit\u00e1rio Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tullia Cuzzi","family":"Teichner","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital Universit\u00e1rio Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle Carvalho","family":"Quintella","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital Universit\u00e1rio Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denize D\u2019Azambuja","family":"Ramos","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital Universit\u00e1rio Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliana de S\u00e1 Freire 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