{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T09:09:05Z","timestamp":1784020145197,"version":"3.55.0"},"reference-count":34,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T00:00:00Z","timestamp":1751241600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the efficacy of ultrawide field fundus photography (UWFFP) in detecting diabetic neovascularization, with a comparative analysis against ultrawide field fluorescein angiography (UWFFA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective cross-sectional study was conducted using images from 100 eyes of 62 treatment-na\u00efve patients with proliferative diabetic retinopathy (PDR), all of whom underwent both UWFFP and UWFFA on the same day. Two masked graders independently evaluated the UWFFP images to identify neovascular lesions, which were categorized into three predefined anatomical zones: neovascularization of the disc (NVD), neovascularization of the mid-periphery (NV-MP; within 10\u2005mm of the fovea), and neovascularization of the far periphery (NV-FP; beyond 10\u2005mm from the fovea). The findings were subsequently compared with those obtained from UWFFA. Sensitivity and specificity analyses were conducted to evaluate differences in detection rates between the two methods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      UWFFP detected NVD and NV-MP effectively, with the highest specificity for NVD (98.2%) and a high sensitivity for NV-MP (90.2%). Strong agreement with UWFFA was observed for NVD (\n                      <jats:italic toggle=\"yes\">\u03ba<\/jats:italic>\n                      \u2009=\u20090.83) and moderate agreement for NV-MP (\n                      <jats:italic toggle=\"yes\">\u03ba<\/jats:italic>\n                      \u2009=\u20090.65). However, UWFFP had lower sensitivity for NV-FP (56.5%) and only moderate agreement (\n                      <jats:italic toggle=\"yes\">\u03ba<\/jats:italic>\n                      \u2009=\u20090.52). McNemar's test showed UWFFA had significantly higher detection rates for NV-FP (46% vs. 29%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>UWFFP is a valuable tool for identifying neovascularization associated with diabetic retinopathy in the optic disc and mid-peripheral retina. However, UWFFA remains the superior modality for reliable assessment, particularly in detecting peripheral neovascularization.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721251349042","type":"journal-article","created":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T06:30:42Z","timestamp":1751265042000},"page":"2229-2234","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Accuracy of ultra-wide field fundus photography for identifying diabetic retinal neovascularization compared to fluorescein angiography"],"prefix":"10.1177","volume":"35","author":[{"given":"Rabab A","family":"Mahmoud","sequence":"first","affiliation":[{"name":"Ophthalmology department, Faculty of medicine, Ain Shams University, Cairo, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7866-7273","authenticated-orcid":false,"given":"Weam M","family":"Ebeid","sequence":"additional","affiliation":[{"name":"Ophthalmology department, Faculty of medicine, Ain Shams University, Cairo, Egypt"},{"name":"Forces College of Medicine, Cairo, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8397-5828","authenticated-orcid":false,"given":"Rania G","family":"Estawro","sequence":"additional","affiliation":[{"name":"Watany Eye Hospital, Cairo, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,6,30]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2022.1047608"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-36327-6"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(13)38011-7"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.15217"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(13)38012-9"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(13)38014-2"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40942-019-0170-2"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S462223"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_1403_20"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.oret.2019.05.007"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1177\/2515841419899495"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2016.01.045"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11892-021-01398-0"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.13-13738"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.xops.2021.100029"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S135287"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.oret.2019.03.007"},{"key":"e_1_3_2_19_2","first-page":"1413\u20131417","article-title":"Comparison of Optomap ultrawide-field imaging versus slit-lamp biomicroscopy for assessment of diabetic retinopathy in a real-life clinic","author":"Purbrick R","unstructured":"Purbrick R, Izadi S, Gupta A, et al. Comparison of Optomap ultrawide-field imaging versus slit-lamp biomicroscopy for assessment of diabetic retinopathy in a real-life clinic. 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