{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:14:49Z","timestamp":1791224089143,"version":"4.1.0"},"reference-count":51,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T00:00:00Z","timestamp":1752710400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To examine potential risk factors of late intraocular lens displacement (LIOLD); a rare complication of cataract surgery believed to be due to progressive zonular insufficiency which is often managed with pars plana vitrectomy (PPV) and intraocular lens (IOL) exchange.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>16 centers across the UK, Germany and Greece<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective case control study<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Cases of LIOLD occurring between June 2018 and January 2023 were identified. Demographics, biometry data, previous medical and ocular history were interrogated and multivariate logistic regression was performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      434 eyes experiencing LIOLD were identified. 20,321 eyes not experiencing LIOLD during the same period formed the control group. Following multivariate analysis, YAG capsulotomy (OR 17.17, 95% CI 12.44\u201323.70,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001), pseudoexfoliation (OR 15.63, 95% CI 10.78\u201322.64,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001), complicated cataract surgery (OR 17.60, 95% CI 12.94\u201323.95,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001), previous PPV (OR 4.86, 95% CI 3.50\u20136.75,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001), younger age at cataract surgery (OR 0.94, 95% CI 0.93\u20130.95,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and axial myopia (OR 1.16, 95% CI 1.09\u20131.24,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001) were identified as risk factors. Female sex was associated with reduced risk (OR 0.64, 95% CI 0.51\u20130.80,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Patients having cataract surgery under 60 years had an increased risk (40 years OR 2.90, 30 years OR 4.92).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Risk factors are known to vary by geographical location and our study being the first multinational study provides a significant contribution. Future studies may look at prevention for at-risk individuals and compare outcomes of different IOL fixation techniques.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721251358006","type":"journal-article","created":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T06:10:51Z","timestamp":1752819051000},"page":"2001-2009","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Risk factors of late intraocular Lens displacement: A multi-national study"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5139-3578","authenticated-orcid":false,"given":"Chimwemwe","family":"Chipeta","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Mid &amp; South Essex NHS Foundation Trust (Southend University Hospital NHS Foundation Trust), Essex, UK"},{"name":"Anglia Ruskin 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