{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:18:52Z","timestamp":1777580332765,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T00:00:00Z","timestamp":1753920000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">\n                        iStent inject\n                        <jats:sup>\u00ae<\/jats:sup>\n                        W\n                      <\/jats:italic>\n                      is a minimally invasive surgical device aimed at creating an alternative trabecular drainage of aqueous humour, reducing intraocular pressure (IOP). International reports already support efficacy and safety, but evidence is lacking about the early-stage learning curve for this device.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>This research was conducted in a teaching tertiary hospital in Lisbon, Portugal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>\n                      Retrospective study on the first 6\n                      <jats:italic toggle=\"yes\">\n                        iStent inject\n                        <jats:sup>\u00ae<\/jats:sup>\n                        W\n                      <\/jats:italic>\n                      implants performed by 6 certified ophthalmic surgeons.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      All procedures were combined with cataract surgery (phaco\u2009+\u2009iStent inject\n                      <jats:sup>\u00ae<\/jats:sup>\n                      W). Primary outcome was total surgical time. Secondary outcomes were complications and postoperative IOP. Outcome data were collected preoperatively and at postoperative days 1, 7, 30, and 90.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Thirty-six patients were included (58% female). Mean age was 73.28\u2009\u00b1\u20099.65 years. Mean surgical time of first surgery was 35.16\u2005min (range 20 to 55), with surgical time decreasing by 8.5\u2005min throughout the learning curve. Mean preoperative IOP was 21.81\u2009\u00b1\u20094.74\u2005mmHg with a mean need of 2 medications. At 1-month, mean IOP was 16.00\u2009\u00b1\u20093.12\u2005mmHg (\u221226.64% than baseline) while resorting to less medication (2.00\u2009\u00b1\u20090.94 to 0.66\u2009\u00b1\u20090.95;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.01). Trabecular meshwork haemorrhage was the most common intra-operative complication reported, and no surgical complications requiring secondary intervention were recorded.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">\n                        iStent inject\n                        <jats:sup>\u00ae<\/jats:sup>\n                        W\n                      <\/jats:italic>\n                      was perceived as a fast-learning procedure, with a significant safety profile in the first cases. The magnitude of IOP reduction of this combined procedure makes it an interesting approach to the glaucoma patient requiring cataract surgery, performed either by a resident under supervision or a glaucoma consultant.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721251363047","type":"journal-article","created":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T08:21:34Z","timestamp":1753950094000},"page":"105-111","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Phaco\u2009+\u2009iStent implant learning curve in a teaching hospital"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6929-4524","authenticated-orcid":false,"given":"Diogo","family":"Bernardo Matos","sequence":"first","affiliation":[{"name":"Servi\u00e7o de Oftalmologia - Unidade Local de Sa\u00fade Santa Maria, Centro Hospitalar Universit\u00e1rio Lisboa Norte \u2013 Hospital Santa Maria"},{"name":"Instituto de Sa\u00fade Ambiental, Faculdade de Medicina, Universidade de Lisboa - Vision Lab, Centro de Estudos das Ci\u00eancias da Vis\u00e3o, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3102-1969","authenticated-orcid":false,"given":"Rafael Correia","family":"Bar\u00e3o","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Oftalmologia - Unidade Local de Sa\u00fade Santa Maria, Centro Hospitalar Universit\u00e1rio Lisboa Norte \u2013 Hospital Santa Maria"},{"name":"Instituto de Sa\u00fade Ambiental, Faculdade de Medicina, Universidade de Lisboa - Vision Lab, Centro de Estudos das Ci\u00eancias da Vis\u00e3o, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuno Pinto","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Oftalmologia - Unidade Local de Sa\u00fade Santa Maria, Centro Hospitalar Universit\u00e1rio Lisboa Norte \u2013 Hospital Santa Maria"},{"name":"Instituto de Sa\u00fade Ambiental, Faculdade de Medicina, Universidade de Lisboa - Vision Lab, Centro de Estudos das Ci\u00eancias da Vis\u00e3o, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riccardo","family":"Peschiera","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Oftalmologia - Unidade Local de Sa\u00fade Santa Maria, Centro Hospitalar Universit\u00e1rio Lisboa Norte \u2013 Hospital Santa Maria"},{"name":"Department of Ophthalmology, ASST Garda \u2013 Ospedale di Desenzano del Garda, Desenzano del Garda, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Afonso","family":"Cabrita","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Oftalmologia - Unidade Local de Sa\u00fade Santa Maria, Centro Hospitalar Universit\u00e1rio Lisboa Norte \u2013 Hospital Santa Maria"},{"name":"Instituto de Sa\u00fade Ambiental, Faculdade de Medicina, Universidade de Lisboa - Vision Lab, Centro de Estudos das Ci\u00eancias da Vis\u00e3o, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno","family":"Dias","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Oftalmologia - Unidade Local de Sa\u00fade Santa Maria, Centro Hospitalar Universit\u00e1rio Lisboa Norte \u2013 Hospital Santa Maria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9 Diogo","family":"Barata","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Oftalmologia - Unidade Local de Sa\u00fade Santa Maria, Centro Hospitalar Universit\u00e1rio Lisboa Norte \u2013 Hospital Santa Maria"},{"name":"Instituto de Sa\u00fade Ambiental, Faculdade de Medicina, Universidade de Lisboa - Vision Lab, Centro de Estudos das Ci\u00eancias da Vis\u00e3o, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9960-7579","authenticated-orcid":false,"given":"Lu\u00eds","family":"Abeg\u00e3o Pinto","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Oftalmologia - Unidade Local de Sa\u00fade Santa Maria, Centro Hospitalar Universit\u00e1rio Lisboa Norte \u2013 Hospital Santa Maria"},{"name":"Instituto de Sa\u00fade Ambiental, Faculdade de Medicina, Universidade de Lisboa - Vision Lab, Centro de Estudos das Ci\u00eancias da Vis\u00e3o, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,7,31]]},"reference":[{"key":"e_1_3_2_2_2","article-title":"Global causes of blindness and distance vision impairment 1990\u20132020: a systematic review and meta-analysis","volume":"5","author":"Flaxman SR","year":"2017","unstructured":"Flaxman SR, Bourne RRA, Resnikoff S, et al. Global causes of blindness and distance vision impairment 1990\u20132020: a systematic review and meta-analysis. Lancet Glob Heal 2017; 5: e1221\u2013e1234.","journal-title":"Lancet Glob Heal"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0000000000001107"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0132048"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-023-06039-8"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0000000000000668"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/ceo.13989"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-021-01687-8"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-021-01595-x"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2021.2351"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40662-019-0157-y"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.3192"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0000000000000623"},{"key":"e_1_3_2_14_2","first-page":"140","article-title":"Application of cataract surgery in the management of glaucoma","volume":"38","author":"Zhang X","year":"2020","unstructured":"Zhang X. Application of cataract surgery in the management of glaucoma. Chinese J Exp Ophthalmol 2020; 38: 140\u2013144.","journal-title":"Chinese J Exp Ophthalmol"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0000000000000444"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2023.02.014"},{"key":"e_1_3_2_17_2","doi-asserted-by":"crossref","unstructured":"Conlon R Saheb H Ahmed IIK. Glaucoma treatment trends: a review. 2020: 1\u201311. doi:https:\/\/doi.org\/10.1016\/j.jcjo.2016.07.013","DOI":"10.1016\/j.jcjo.2016.07.013"},{"key":"e_1_3_2_18_2","doi-asserted-by":"crossref","unstructured":"Shalaby WS Jia J Katz LJ et al. iStent inject: comprehensive review. 2020: 385\u2013399.","DOI":"10.1097\/j.jcrs.0000000000000325"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2019.04.034"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0000000000001484"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/2731856"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2019.07.021"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/8754730"},{"key":"e_1_3_2_24_2","first-page":"1","article-title":"Symposium recent advances and challenges in the management of retinoblastoma globe - saving treatments","volume":"17","author":"Balasopoulou A","year":"2017","unstructured":"Balasopoulou A, \u039aokkinos P, Pagoulatos D, et al. Symposium recent advances and challenges in the management of retinoblastoma globe - saving treatments. BMC Ophthalmol 2017; 17: 1.","journal-title":"BMC Ophthalmol"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10078-1414"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11206721251363047","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/11206721251363047","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11206721251363047","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:41:32Z","timestamp":1777405292000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/11206721251363047"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,31]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1177\/11206721251363047"],"URL":"https:\/\/doi.org\/10.1177\/11206721251363047","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,31]]}}}