{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:18:53Z","timestamp":1777580333592,"version":"3.51.4"},"reference-count":47,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T00:00:00Z","timestamp":1754870400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To compare the corneal biomechanical characteristics following accelerated cross-linking (A-CXL) and diluted alcohol and iontophoresis-assisted corneal cross-linking (DAI-CXL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Forty-nine eyes from 41 patients who underwent DAI-CXL or A-CXL for progressive keratoconus were included. Visual acuity, topographic, and biomechanical data were analyzed preoperatively and 12 months postoperatively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A significant decrease in flat keratometry (K1) and thinnest corneal thickness (TCT) was observed in the A-CXL group between baseline and postoperatively (K1,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.001; TCT:\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.007). Both groups showed a significant decrease in steep keratometry (K2) and maximum keratometry (Kmax) compared to baseline (K2:\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.03,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001, respectively; Kmax:\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001 for both groups). Postoperatively, highest concavity time (HCT) was significantly lower (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.007), and highest concavity peak distance (HCPD) was significantly higher (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.034) in the DAI-CXL group compared to the A-CXL group. A significant increase in applanation 1 velocity (A1V), HCPD, and deformation amplitude (DA) (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.03, 0.007, 0.02, respectively) and a decrease in Ambr\u00f3sio relational thickness to the horizontal profile (ARTh) (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001) were noted in the A-CXL group at 12 months. The DAI-CXL group showed a significant decrease in HCT, integrated radius (IR), and ARTh (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.006, 0.011, 0.009, respectively) between baseline and postoperative assessments. Corvis Biomechanical Factor (CBiF) and E-stage remained stable in both groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>DAI-CXL and A-CXL demonstrate comparable efficacy in achieving visual, topographic, and biomechanical stabilization in progressive keratoconus over a 12-month period.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721251364409","type":"journal-article","created":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T07:03:08Z","timestamp":1754895788000},"page":"24-33","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Topographic and biomechanical comparison of diluted alcohol and iontophoresis-assisted versus accelerated corneal crosslinking in keratoconus"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8710-8871","authenticated-orcid":false,"given":"Caglar","family":"Bektas","sequence":"first","affiliation":[{"name":"Canakkale Onsekiz Mart University Faculty of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6357-877X","authenticated-orcid":false,"given":"Betul Seher","family":"Uysal","sequence":"additional","affiliation":[{"name":"Gazi University Faculty of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasan","family":"Diker","sequence":"additional","affiliation":[{"name":"Gazi University Faculty of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet Cuneyt","family":"Ozmen","sequence":"additional","affiliation":[{"name":"Gazi University Faculty of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamil","family":"Bilgihan","sequence":"additional","affiliation":[{"name":"Gazi University Faculty of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,8,11]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2003.06.020"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2020.108328"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2019.2058"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(02)02220-1"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1006\/exer.1997.0410"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/aos.13814"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000002092"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2009.03.035"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.3109\/08820538.2014.962176"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e31824d6fe3"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2013.11.018"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20141021-06"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.3109\/02713683.2011.637656"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2021.05.009"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000001383"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000002821"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2006.03.015"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2004.10.044"},{"key":"e_1_3_2_20_2","article-title":"Corneal deformation measurement using scheimpflug noncontact tonometry","volume":"90","author":"Hon Y","year":"2013","unstructured":"Hon Y, Lam AKC. 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