{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:18:57Z","timestamp":1777580337940,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100001818","name":"Research to Prevent Blindness","doi-asserted-by":"publisher","award":["NA"],"award-info":[{"award-number":["NA"]}],"id":[{"id":"10.13039\/100001818","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the outcome of PPV in PDR patients with a Light Perception (LP) visual acuity at the time of signing up for surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study reviewed patient records from Harbor-UCLA and Olive View Medical Centers between March 2018 and March 2022. 32 patients (32 eyes) with LP visual acuity prior to surgery were included. Preoperative, intraoperative, and postoperative data were collected. Visual outcomes were assessed at 3 months (POM3), 6 months (POM6), and final follow-up. Statistical analyses included paired T-tests for visual acuity comparisons, linear regression for outcome predictors, and logistic regression for macular detachment risk factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Significant visual improvement at POM3 (BCVA 20\/660) and POM6 (BCVA 20\/890) were observed compared to baseline, with a final follow-up BCVA of 20\/600. At final follow-up, 37.5% of patients showed no improvement, with 12.5% experiencing No Light Perception (NLP). Multivariable analysis identified longer surgical duration as a significant negative predictor of achieving BCVA of 20\/100 or better. Preoperative rhegmatogenous retinal detachment and a higher number of prior vitrectomies were associated with lower odds of maintaining retinal attachment at 6 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>PPV provides a significant improvement in visual acuity for many patients with advanced PDR. However, a substantial portion of patients experience minimal or no improvement. Identified predictors of poorer outcomes can guide preoperative counseling and decision-making. This study highlights the need for careful consideration of surgical risks and benefits in advanced PDR cases.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721251367572","type":"journal-article","created":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T07:25:55Z","timestamp":1754983555000},"page":"112-118","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Vitrectomy in eyes with diabetic retinopathy and light perception vision: A comprehensive outcome analysis"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2737-8818","authenticated-orcid":false,"given":"Reza","family":"Kianian","sequence":"first","affiliation":[{"name":"Emory University School of Medicine"},{"name":"Stein Eye Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weilin","family":"Song","sequence":"additional","affiliation":[{"name":"Stein Eye Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judy","family":"Figueroa","sequence":"additional","affiliation":[{"name":"Stein Eye Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deyu","family":"Sun","sequence":"additional","affiliation":[{"name":"Stein Eye Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jack B.","family":"Margines","sequence":"additional","affiliation":[{"name":"Stein Eye Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiwei","family":"Sheng","sequence":"additional","affiliation":[{"name":"Stein Eye Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirk","family":"Hou","sequence":"additional","affiliation":[{"name":"Stein Eye Institute"},{"name":"Olive View \u2013 UCLA Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pradeep","family":"Prasad","sequence":"additional","affiliation":[{"name":"Stein Eye Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamid","family":"Hosseini","sequence":"additional","affiliation":[{"name":"Stein Eye Institute"},{"name":"Harbor \u2013 UCLA Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,8,12]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13167-023-00314-8"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecl.2021.05.005"},{"key":"e_1_3_2_4_2","first-page":"302","article-title":"Prevalence of diabetic retinopathy, proliferative diabetic retinopathy and non-proliferative diabetic retinopathy in Asian T2DM patients: a systematic review and meta-analysis","volume":"12","author":"Yang QH","year":"2019","unstructured":"Yang QH, Zhang Y, Zhang XM, et al. Prevalence of diabetic retinopathy, proliferative diabetic retinopathy and non-proliferative diabetic retinopathy in Asian T2DM patients: a systematic review and meta-analysis. Int J Ophthalmol 2019; 12: 302\u2013311.","journal-title":"Int J Ophthalmol"},{"key":"e_1_3_2_5_2","volume-title":"StatPearls [Internet]","author":"Omari A","year":"2024","unstructured":"Omari A, Mahmoud TH. Vitrectomy. In: StatPearls [Internet]. Treasure Island, FL: StatPearls Publishing, 2024. [cited 2024 Oct 10]. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/31869132\/"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S400474"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/9481902"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11185399"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/aos.14659"},{"key":"e_1_3_2_10_2","unstructured":"U.S. Department of Health & Human Services. Diabetes and Hispanic Americans [Internet]. 2024. [cited 2024 Oct 8]. Available from: https:\/\/minorityhealth.hhs.gov\/diabetes-and-hispanic-americans"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2004.03.002"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.12419"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.oret.2020.08.001"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e31805d0bfb"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/7691724"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9103251"},{"key":"e_1_3_2_17_2","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1167\/tvst.11.8.25","article-title":"Prediction of visual outcomes after diabetic vitrectomy using clinical factors from common data warehouse","volume":"11","author":"Lee SS","year":"2022","unstructured":"Lee SS, Chang DJ, Kwon JW, et al. Prediction of visual outcomes after diabetic vitrectomy using clinical factors from common data warehouse. Transl Vis Sci Technol 2022; 11: 25.","journal-title":"Transl Vis Sci Technol"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1159\/000514538"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e3181e7974f"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2010.190314"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2011-300581"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/269837"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1328392"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e3182877a27"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2007.129437"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-008-0997-y"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11206721251367572","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/11206721251367572","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11206721251367572","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:41:34Z","timestamp":1777405294000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/11206721251367572"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,12]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1177\/11206721251367572"],"URL":"https:\/\/doi.org\/10.1177\/11206721251367572","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,12]]}}}