{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:19:46Z","timestamp":1777580386396,"version":"3.51.4"},"reference-count":46,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:00:00Z","timestamp":1765756800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>This study evaluated and compared changes in pachymetry measurements at different times after applying riboflavin 0.25%, lissamine green 0.5%, fluorescein 2%, and fluorescein 0.25% - lidocaine HCl 4% eye drops.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Corneal pachymetry was assessed in thirty healthy volunteers (60 eyes) using a Galilei G6\n                      <jats:sup>\u00ae<\/jats:sup>\n                      Dual Scheimpflug topographer. Baseline measurements were taken with and without saline. Thickness was measured at 1, 5, and 15\u2005min after dye application.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Significant increases (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001) in Central Corneal Thickness (CCT) were observed following riboflavin instillation (N\u2009=\u200960, at 1\u2005min: 17\u2009\u00b1\u20097.1\u2005\u00b5m; at 5\u2005min: 7.1\u2009\u00b1\u20096.9\u2005\u00b5m), fluorescein 0.25% (N\u2009=\u200959, at 1\u2005min: 14.8\u2009\u00b1\u200914.1\u2005\u00b5m; at 5\u2005min: 9.4\u2009\u00b1\u20097.4\u2005\u00b5m; at 15\u2005min: 5.2\u2009\u00b1\u20096.7\u2005\u00b5m), and fluorescein 2% (N\u2009=\u200910, at 1\u2005min: 20\u2009\u00b1\u20095.7\u2005\u00b5m; at 5\u2005min: 18.8\u2009\u00b1\u20097\u2005\u00b5m; at 15\u2005min: 11.2\u2009\u00b1\u20098.4\u2005\u00b5m). There was a high number of artifacts in the measurements with 2% fluorescein (48 eyes), and only three patients showed no artifacts. Lissamine green (N\u2009=\u200958) did not significantly affect pachymetry measurements.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Riboflavin 0.25% and fluorescein 0.25% temporarily overestimated pachymetry. Fluorescein 2% caused excessive artifacts, compromising reliability. Lissamine green 0.5% showed no influence in pachymetry. Characteristics from vital dyes should be considered according to programmed examinations when using a Dual Scheimpflug topographer.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721251405522","type":"journal-article","created":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T14:30:56Z","timestamp":1765809056000},"page":"577-585","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of corneal vital dyes on pachymetry measured by dual Scheimpflug technology"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-3093-4310","authenticated-orcid":false,"given":"Ignacio","family":"L\u00f3pez Mi\u00f1arro","sequence":"first","affiliation":[{"name":"Hospital Cl\u00ednico Universitario de Valladolid"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3901-6837","authenticated-orcid":false,"given":"Mar\u00eda","family":"G\u00f3mez Tom\u00e1s","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico Universitario de Valladolid"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-3841-0003","authenticated-orcid":false,"given":"Isabel","family":"Bermejo Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico Universitario de Valladolid"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9992-5801","authenticated-orcid":false,"given":"Pablo","family":"Redruello Guerrero","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico Universitario de Valladolid"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-4018-6276","authenticated-orcid":false,"given":"Laura","family":"Prieto Dom\u00ednguez","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico Universitario de Valladolid"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5649-6971","authenticated-orcid":false,"given":"David J","family":"Galarreta","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico Universitario de Valladolid"},{"name":"Ophtalmology Department, Instituto Oftalmol\u00f3gico Recoletas (IOR), Valladolid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,12,15]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00055735-200008000-00005"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_2137_22"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2013.02.003"},{"key":"e_1_3_2_5_2","article-title":"Clinical tool to measure fluorescein patterns in orthokeratology","volume":"10","author":"Rosuero MLG","year":"2022","unstructured":"Rosuero MLG, Bombin AA, Romero R, et al. 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