{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T10:18:52Z","timestamp":1787653132459,"version":"build-2736575974"},"reference-count":30,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To compare the analgesic efficacy of 2% lidocaine gel and 0.4% oxybuprocaine eye drops in patients undergoing pterygium surgery, focusing on perioperative pain assessed in the early postoperative period and postoperative discomfort over one month.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Sixty-eight adult patients with bilateral primary nasal pterygia underwent two separate surgeries, one in each eye, at least 30 days apart. Each eye was randomly assigned to receive either 2% lidocaine gel or 0.4% oxybuprocaine eye drops for topical anesthesia. Pain perception was evaluated using the Visual Analog Scale (VAS) at 24\u2005h and 30 days after surgery. VAS scores at 24\u2005h reflected early perioperative pain as recalled in the immediate postoperative period, encompassing discomfort related to the surgical experience. Secondary outcomes included oral analgesic use during the first postoperative day and complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Three patients declined second-eye surgery after marked discomfort during the first procedure performed with oxybuprocaine. The final sample comprised 133 eyes (68 eyes with oxybuprocaine, 65 with lidocaine gel). Mean VAS scores were significantly lower in the lidocaine group at 24\u2005h (3.95\u2009\u00b1\u20093.14 vs. 5.09\u2009\u00b1\u20093.06;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.037) and 30 days (1.55\u2009\u00b1\u20092.14 vs. 2.69\u2009\u00b1\u20092.37;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.004). Analgesic intake within 24\u2005h was less frequent with lidocaine gel (7.4% vs. 17.6%;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.145). No complications were observed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Topical 2% lidocaine gel provided superior analgesia compared with 0.4% oxybuprocaine, resulting in lower early perioperative pain assessed postoperatively and reduced postoperative discomfort after pterygium surgery, while maintaining an excellent safety profile.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721261429131","type":"journal-article","created":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T13:42:18Z","timestamp":1773236538000},"page":"1205-1211","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Lidocaine gel provides superior analgesia compared to oxybuprocaine drops in pterygium surgery: A double-masked randomized trial"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3800-2984","authenticated-orcid":false,"given":"Caio Henrique Peres","family":"Oliani","sequence":"first","affiliation":[{"name":"Hospital Vis\u00e3o Laser"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicoli Lopes de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Hospital Vis\u00e3o Laser"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Ant\u00f4nio de","family":"Brito Martins","sequence":"additional","affiliation":[{"name":"Hospital Vis\u00e3o Laser"},{"name":"Department of Ophthalmology and Visual Sciences, Federal University of S\u00e3o Paulo, UNIFESP, Sao Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9812-9050","authenticated-orcid":false,"given":"Sergio","family":"Felberg","sequence":"additional","affiliation":[{"name":"Santa Casa de Misericordia de S\u00e3o Paulo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcello Novoa","family":"Colombo-Barboza","sequence":"additional","affiliation":[{"name":"Hospital Vis\u00e3o Laser"},{"name":"Department of Ophthalmology, Centro Universitario Lusiadas (UNILUS), Santos, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2099-0323","authenticated-orcid":false,"given":"Guilherme Novoa","family":"Colombo-Barboza","sequence":"additional","affiliation":[{"name":"Hospital Vis\u00e3o Laser"},{"name":"Department of Ophthalmology, Universidade Metropolitana de Santos (UNIMES)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4441-4304","authenticated-orcid":false,"given":"Bernardo Kaplan","family":"Moscovici","sequence":"additional","affiliation":[{"name":"Hospital Vis\u00e3o Laser"},{"name":"Department of Ophthalmology and Visual Sciences, Federal University of S\u00e3o Paulo, UNIFESP, Sao Paulo, Brazil"},{"name":"Postgraduate Program in Translational Medicine, Department of Medicine, Escola Paulista de Medicina, Federal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,3,10]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0b013e3182815b2a"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000001451"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000001995"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000002137"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.2005.00404.x"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/5144516"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/acem.14222"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_3055_20"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000001106"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.4103\/1110-9173.157771"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000003317"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aew466"},{"key":"e_1_3_2_14_2","article-title":"Measures of adult pain: VAS, NRS, MPQ, SF-MPQ","volume":"63","author":"Hawker GA","year":"2011","unstructured":"Hawker GA, Mian S, Kendzerska T, et al. 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