{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T18:15:52Z","timestamp":1792606552372,"version":"4.5.0"},"reference-count":25,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:00:00Z","timestamp":1774483200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate whether preoperative systemic inflammatory indices and tear film parameters predict pterygium recurrence after conjunctival autograft (CAG) surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective matched case-control study included 94 eyes (47 with recurrence, 47 controls) matched for age, sex, and pterygium grade. Preoperative neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), and systemic immune-inflammation index (SII) were calculated from complete blood counts. Tear breakup time (TBUT) and Schirmer I test assessed ocular surface function. Between-group differences and logistic regression identified independent predictors, while receiver operating characteristic (ROC) analysis evaluated discriminative performance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patients with recurrence had higher NLR (median 2.5 vs. 1.9, p\u2009&lt;\u20090.001) and SII (600 vs. 450\u2009\u00d7\u200910\n                      <jats:sup>3<\/jats:sup>\n                      , p\u2009&lt;\u20090.01), whereas PLR and MLR showed no significant differences. Tear film parameters were worse in recurrence cases: TBUT (5.0 vs. 8.0\u2005s, p\u2009&lt;\u20090.001) and Schirmer I (8 vs. 12\u2005mm, p\u2009=\u20090.02). Multivariate analysis identified elevated NLR (\u22652.0; OR 4.2, 95% CI 1.4\u201312.8) and reduced Schirmer I (\u226410\u2005mm; OR 3.0, 95% CI 1.1\u20137.9) as independent predictors.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Elevated systemic inflammation and impaired tear function independently predict pterygium recurrence. Incorporating these markers may guide individualized risk assessment and postoperative management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721261436135","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T12:19:25Z","timestamp":1774527565000},"page":"1283-1290","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Preoperative systemic inflammatory indices and tear film parameters as predictors of pterygium recurrence: A matched case-control study"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8731-0471","authenticated-orcid":false,"given":"S\u00fccattin \u0130lker","family":"Kocam\u0131\u015f","sequence":"first","affiliation":[{"name":"Ophthalmology Department, D\u0131\u015fkap\u0131 Y\u0131ld\u0131r\u0131m Beyaz\u0131t Training and Research Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8033-2970","authenticated-orcid":false,"given":"Ecem","family":"Bi\u015fkiner","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, D\u0131\u015fkap\u0131 Y\u0131ld\u0131r\u0131m Beyaz\u0131t Training and Research Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6067-4192","authenticated-orcid":false,"given":"Bedia","family":"Kesimal","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, D\u0131\u015fkap\u0131 Y\u0131ld\u0131r\u0131m Beyaz\u0131t Training and Research Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7401-8903","authenticated-orcid":false,"given":"Aysun \u015eanal","family":"Do\u011fan","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, D\u0131\u015fkap\u0131 Y\u0131ld\u0131r\u0131m Beyaz\u0131t Training and Research Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,3,26]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2018.03.001"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2004.02.002"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.5935\/0004-2749.20190103"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/0394632017742505"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10384-020-00786-5"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(85)33831-9"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-020-0786-3"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2012.06.021"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2017-310288"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2012.06.066"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.4103\/joco.joco_153_20"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000000221"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e318259c934"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1159\/000321531"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1159\/000493544"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.4103\/meajo.meajo_75_21"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-90433-1"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/5744008"},{"key":"e_1_3_3_20_2","first-page":"111","article-title":"Evaluation of neutrophil\u2013lymphocyte ratios, mean platelet volumes, and platelet\u2013lymphocyte ratios in pterygium","volume":"4","author":"G\u00f6kmen O","year":"2019","unstructured":"G\u00f6kmen O. Evaluation of neutrophil\u2013lymphocyte ratios, mean platelet volumes, and platelet\u2013lymphocyte ratios in pterygium. 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