{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T10:18:51Z","timestamp":1787653131060,"version":"build-2736575974"},"reference-count":25,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T00:00:00Z","timestamp":1775088000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the agreement between a virtual clinic model based on ultra-widefield imaging (UWFI) and spectral-domain optical coherence tomography (SD-OCT) and conventional face-to-face (F2F) slit-lamp fundus examination with SD-OCT for treatment decision-making in patients receiving intravitreal injections.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this retrospective masked paired comparative study, consecutive patients receiving intravitreal injections underwent F2F evaluation by a retina specialist using slit-lamp biomicroscopy and SD-OCT. F2F examination was predefined as the reference standard. During the same clinical encounter, UWFI was obtained. A second retina specialist, masked to the clinical findings and decisions, independently reviewed the SD-OCT and UWFI images in a virtual setting and made management decisions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 426 eyes from 304 patients were included. Of these, 217 eyes (50.94%) had neovascular age-related macular degeneration (NVAMD), 151 (35.45%) diabetic macular edema (DME), and 56 (13.15%) retinal vein occlusion (RVO; 36 branch RVO, 14 central RVO, and 6 hemi-retinal RVO). One eye (0.23%) had myopic choroidal neovascularization (CNV), and one (0.23%) had Sorsby macular dystrophy with CNV.<\/jats:p>\n                    <jats:p>\n                      The virtual assessment demonstrated 98.12% agreement with the F2F examination for treatment decisions (Cohen's\n                      <jats:italic toggle=\"yes\">\u03ba<\/jats:italic>\n                      \u2009=\u20090.90; 95% CI, 0.83\u20130.97). Recognition of NVAMD-associated macular hemorrhages was comparable between modalities. UWFI identified additional cases of neovascularization of the disc (NVD) and neovascularization elsewhere (NVE), all of which were subsequently confirmed on slit-lamp examination. The mean virtual review time was more than twofold shorter than the F2F evaluation (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Virtual assessment using ultra-widefield imaging demonstrated high agreement with F2F slit-lamp examination for treatment decision-making in patients receiving intravitreal injections. This approach may represent an efficient alternative for selected follow-up visits in which anterior segment evaluation is not required.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721261438854","type":"journal-article","created":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T14:38:12Z","timestamp":1775140692000},"page":"1400-1407","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessing patients who are treated with intravitreal injections by ultra-wide field imaging versus slit lamp biomicroscopy"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-9755-182X","authenticated-orcid":false,"given":"Gilad","family":"Allon","sequence":"first","affiliation":[{"name":"Meir Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geva","family":"Sarrabia","sequence":"additional","affiliation":[{"name":"Meir Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee","family":"Goren","sequence":"additional","affiliation":[{"name":"Rabin Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elad","family":"Moisseiev","sequence":"additional","affiliation":[{"name":"Meir Medical Center"},{"name":"Tel Aviv University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ori","family":"Segal","sequence":"additional","affiliation":[{"name":"Meir Medical Center"},{"name":"Tel Aviv 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