{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T10:18:53Z","timestamp":1787653133091,"version":"build-2736575974"},"reference-count":19,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T00:00:00Z","timestamp":1779148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Epithelial inclusion cysts of the iris are a rare complication following ocular surgery or trauma and typically exhibit a more aggressive course than other types of iris cysts. Their management remains challenging due to their tendency for rapid growth, which can lead to obscuration of the visual axis, elevated intraocular pressure, corneal decompensation, and secondary glaucoma or uveitis. Particularly in pediatric and young adult patients, the high proliferative capacity of epithelial cells increases the risk of recurrence. Current treatment modalities, including Nd:YAG laser cyst disruption, sclerosing agent irrigation, and complete surgical excision, are associated with high recurrence rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this retrospective case series we describe two patients with a recurrent iris cyst resulting from a trauma in childhood, and successfully managed with glaucoma drainage devices (Baerveldt tube and PAUL tube) to provide continuous cyst fluid drainage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In both cases, implantation of the drainage device effectively controlled the progression of the cyst and maintained its position outside the visual axis. The pediatric patient developed a scleral perforation at the surgical site one year postoperatively, following additional mechanical trauma from ocular rubbing; this complication was successfully managed with surgical repair, resulting in a favorable outcome. In the second case, the patient experienced a transient postoperative diplopia, which resolved spontaneously without further intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These cases illustrate the potentially promising role of glaucoma drainage devices as a new treatment strategy for recurrent iris cysts, particularly after multiple prior resections or when conventional therapies have failed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721261453629","type":"journal-article","created":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T14:31:06Z","timestamp":1779201066000},"page":"1464-1469","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Glaucoma drainage devices as a novel treatment option in the management of recurrent iris cysts"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4685-5616","authenticated-orcid":false,"given":"Tom","family":"Collignon","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, University Hospitals Leuven"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Cassiman","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Hospitals Leuven"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Saelens","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Hospitals Leuven"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingeborg","family":"Stalmans","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Hospitals Leuven"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heleen","family":"Delbeke","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Hospitals Leuven"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,19]]},"reference":[{"key":"e_1_3_4_2_2","first-page":"771","article-title":"Primary cysts of the iris","volume":"79","author":"Shields JA","year":"1981","unstructured":"Shields JA. Primary cysts of the iris. Trans Am Ophthalmol Soc 1981; 79: 771\u2013809.","journal-title":"Trans Am Ophthalmol Soc"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2017.08.009"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2018-312738"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(03)00543-8"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mjafi.2013.04.001"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.123.9.1276"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(85)34040-X"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(02)01960-8"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2014.160"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.84.7.799b"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.4103\/IJO.IJO_2897_23"},{"key":"e_1_3_4_13_2","first-page":"375947","article-title":"The diagnostic and therapeutic challenges of posttraumatic Iris implantation cysts: illustrative case presentations and a review of the literature","volume":"2015","author":"Venkateswaran N","year":"2015","unstructured":"Venkateswaran N, Ching SS, Fischer W, et al. The diagnostic and therapeutic challenges of posttraumatic Iris implantation cysts: illustrative case presentations and a review of the literature. 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