{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:13:07Z","timestamp":1777579987778,"version":"3.51.4"},"reference-count":41,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1992,1,1]],"date-time":"1992-01-01T00:00:00Z","timestamp":694224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[1992,1]]},"abstract":"<jats:p>In 1958, Kearns and Sayre described a multisystem entity, now known as Kearns-Sayre syndrome (KSS). The syndrome is defined as exhibiting a triad of thus far unexplained degenerative conditions: progressive external ophthalmoplegia, retinal pigmentary degeneration, and heart block. Commonly accompanying findings include cerebellar dysfunction and CSF protein levels above 100 mg\/dl. Symptoms usually appear in early childhood, but the onset has been seen occasionally in young adults. KSS is a mitochondrial disorder that occurs rarely; the actual incidence is unknown. Ocular findings consist of bilateral ptosis, chronic progressive external ophthalmoplegia, and pigmentary retinopathy. Corneal clouding and optic neuritis are infrequent.<\/jats:p>\n                  <jats:p>We herein report a classic case of Kearns Sayre syndrome and discuss the findings.<\/jats:p>","DOI":"10.1177\/112067219200200104","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T11:11:14Z","timestamp":1523877074000},"page":"15-20","source":"Crossref","is-referenced-by-count":13,"title":["Kearns-Sayre Syndrome: A Case Report and Review"],"prefix":"10.1177","volume":"2","author":[{"given":"M.","family":"Gross-Jendroska","sequence":"first","affiliation":[{"name":"Free University of Berlin, Berlin - Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Schatz","sequence":"additional","affiliation":[{"name":"Wayne and Gladys Valley Foundation, San Ramon, California - U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.R.","family":"Mcdonald","sequence":"additional","affiliation":[{"name":"Wayne and Gladys Valley Foundation, San Ramon, California - U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.N.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Wayne and Gladys Valley Foundation, San Ramon, California - U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1992,1,1]]},"reference":[{"key":"bibr1-112067219200200104","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1958.00940080296016"},{"key":"bibr2-112067219200200104","first-page":"559","volume":"63","author":"Kearns T.P.","year":"1965","journal-title":"Trans Am Ophthalmol 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