{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:20:38Z","timestamp":1777580438994,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1996,10,1]],"date-time":"1996-10-01T00:00:00Z","timestamp":844128000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[1996,10]]},"abstract":"<jats:p>\n                    The effects of four days\u2019 treatment with topical Maxitrol\n                    <jats:sup>\u00ae<\/jats:sup>\n                    (neomycin sulphate 3500 lU\/mL, polymyxin-B sulphate 6000 lU\/mL with dexamethasone 0.1%) were compared with those of Maxidex\n                    <jats:sup>\u00ae<\/jats:sup>\n                    (dexamethasone 0.1% alone) in a double-masked study in 111 patients with bacterial blepharitis or conjunctivitis, 95 of whom were evaluable for efficacy. The majority of patients (N=80) had chronic blepharitis. Maxitrol treatment resulted in a significantly greater reduction (90%) in bacterial counts and bacterial eradication (50%) compared with Maxidex (34% and 17% respectively). Maxitrol treatment also produced a significantly greater reduction in conjunctival discharge than did Maxidex, while the treatments were equally effective in alleviating other ocular signs and symptoms. It was concluded that use of a fixed dose combination steroid-antibiotic product was more effective for bacterial control and therapeutic efficacy in the treatment of chronic blepharitis and conjunctivitis patients than treatment with steroid alone. However, in the long-term treatment of chronic blepharitis the well-known toxic problems of neomycin sulphate have to be taken into account.\n                  <\/jats:p>","DOI":"10.1177\/112067219600600403","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T11:16:06Z","timestamp":1523877366000},"page":"361-367","source":"Crossref","is-referenced-by-count":17,"title":["Comparative Evaluation of the Short-Term Bactericidal Potential of a Steroid-Antibiotic Combination versus Steroid in the Treatment of Chronic Bacterial Blepharitis and Conjunctivitis"],"prefix":"10.1177","volume":"6","author":[{"given":"D.G.","family":"Shulman","sequence":"first","affiliation":[{"name":"San Antonio, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.B.","family":"Sargent","sequence":"additional","affiliation":[{"name":"Eye Care, Austin, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.H.","family":"Stewart","sequence":"additional","affiliation":[{"name":"Houston Eye Associates, Houston, Texas - U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"Mester","sequence":"additional","affiliation":[{"name":"Bundesknappschafts Hospital, Sulzbach, Saar - Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1996,10,1]]},"reference":[{"key":"bibr1-112067219600600403","first-page":"45","volume-title":"Infections of the Eye, 1st ed.","author":"Chusid M.J.","year":"1986"},{"key":"bibr2-112067219600600403","first-page":"103","volume-title":"Grayson's Diseases of the Cornea, 3rd ed. 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