{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T06:33:49Z","timestamp":1777617229611,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1997,1,1]],"date-time":"1997-01-01T00:00:00Z","timestamp":852076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[1997,1]]},"abstract":"<jats:p>The aim of the study was to evaluate the effect of mitomycin-C (MMC) in a second antiglaucoma operation after failure of the first operation. We assessed 46 patients (26 male, 20 female, mean age 64.2 years) with high intraocular pressure (IOP) (mean 32.4 \u00b1 5.2 mmHg) despite previous trabeculectomy (Tr-Ec) one to three years earlier and topical or systemic medical treatment. All patients underwent a second Tr-Ec and were randomly divided into two groups: group A, 24 patients, underwent a second Tr-Ec with MMC and group B, 22 patients, also underwent a second Tr-Ec but without MMC.<\/jats:p>\n                  <jats:p>Postoperative complications included: shallow anterior chamber (duration &gt;1 week), group A 29.2%, group B 13.6%; chroidal effusion, group A 8.3%, group B 0%; cystic degeneration of conjunctiva, group A 16.6%, group B 4.5%; transient maculopathy, group A 12.5%, group B 0%. IOP control (\u2264 20 mmHg after 18 months) was: group A 20 patients (83.3%) with mean 12.5 \u00b1 3.2 mmHg and group B 13 patients (63.6%) with mean 19.6 \u00b1 6.1 mmHg.<\/jats:p>\n                  <jats:p>In conclusion, the use of MMC in re-operation for primary open-angle glaucoma is associated with a higher rate of and more severe postoperative complications than Tr-Ec alone. However, it achieves significantly lower IOP in a larger number of patients.<\/jats:p>","DOI":"10.1177\/112067219700700109","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T11:10:43Z","timestamp":1523877043000},"page":"49-54","source":"Crossref","is-referenced-by-count":25,"title":["Clinical Evaluation of the Effect of Mitomycin-C in Re-Operation for Primary Open Angle Glaucoma"],"prefix":"10.1177","volume":"7","author":[{"given":"D.","family":"Andreanos","sequence":"first","affiliation":[{"name":"Department of Glaucoma, University Eye Clinic of Athens, Athens - Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.T.","family":"Georgopoulos","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, University Eye Clinic of Athens, Athens - Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Vergados","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, University Eye Clinic of Athens, Athens - Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Papaconstantinou","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, University Eye Clinic of Athens, Athens - Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Liokis","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, University Eye Clinic of Athens, Athens - Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Theodossiadis","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, University Eye Clinic of Athens, Athens - Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1997,1,1]]},"reference":[{"key":"bibr1-112067219700700109","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)71349-2"},{"key":"bibr2-112067219700700109","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(91)32293-0"},{"key":"bibr3-112067219700700109","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(92)31951-7"},{"key":"bibr4-112067219700700109","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.77.11.693"},{"key":"bibr5-112067219700700109","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)73465-8"},{"key":"bibr6-112067219700700109","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(92)31781-6"},{"key":"bibr7-112067219700700109","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(95)31049-4"},{"key":"bibr8-112067219700700109","first-page":"612","volume":"24","author":"Neelakantan A.","year":"1994","journal-title":"Ophthalmic Surg"},{"key":"bibr9-112067219700700109","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1993.01090020117035"},{"key":"bibr10-112067219700700109","doi-asserted-by":"publisher","DOI":"10.1006\/exer.1994.1080"},{"key":"bibr11-112067219700700109","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)72957-5"},{"key":"bibr12-112067219700700109","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)73810-3"},{"key":"bibr13-112067219700700109","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(93)31442-9"},{"key":"bibr14-112067219700700109","doi-asserted-by":"publisher","DOI":"10.1038\/eye.1993.149"},{"key":"bibr15-112067219700700109","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)72903-4"},{"key":"bibr16-112067219700700109","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1991.01080120077030"},{"key":"bibr17-112067219700700109","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.1994.tb02780.x"},{"key":"bibr18-112067219700700109","doi-asserted-by":"publisher","DOI":"10.1007\/BF00915967"},{"key":"bibr19-112067219700700109","first-page":"164","volume":"3","author":"Mietz H.","year":"1994","journal-title":"Ger J Ophthalmol"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/112067219700700109","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/112067219700700109","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:42:29Z","timestamp":1777405349000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/112067219700700109"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,1]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1997,1]]}},"alternative-id":["10.1177\/112067219700700109"],"URL":"https:\/\/doi.org\/10.1177\/112067219700700109","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,1]]}}}