{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:21:45Z","timestamp":1777580505784,"version":"3.51.4"},"reference-count":44,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1997,10,1]],"date-time":"1997-10-01T00:00:00Z","timestamp":875664000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[1997,10]]},"abstract":"<jats:p>The aim of the study was to determine whether certain factors are related to an increased risk of developing open-angle glaucoma. A total of 345 untreated glaucoma suspects with intraocular pressure (IOP) \u2265 21 mmHg, cup to disc ratio 0.4 or less and no visual field defects, were followed up for 6 to 8 years (mean 7.3). During the follow-up 71 patients developed established glaucoma and were compared to the remaining 274 patients. The following factors were analysed: age, family history of glaucoma, IOP, Humphrey 30-2 visual fields, optic disc appearance, myopia, exfoliation, arterial hypertension and diabetes. Analysis yielded statistically significant results regarding a number of these factors in the patients who subsequently developed open-angle glaucoma. A significant association with the subsequent development of field loss in ocular hypertension (OHT) included: heredity (p &lt; 0.001), age \u2265 60 years (p = 0.013), axial myopia (0.001 &lt; p &lt; 0.01) and arterial hypertension (p = 0.05). About 20% of patients with ocular hypertension developed glaucoma over a period of seven years. Risk factors such as heredity, age, myopia and arterial hypertension, among others, must be considered in the follow-up of glaucoma suspects.<\/jats:p>","DOI":"10.1177\/112067219700700409","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T11:10:23Z","timestamp":1523877023000},"page":"357-363","source":"Crossref","is-referenced-by-count":31,"title":["Risk Factors in Ocular Hypertension"],"prefix":"10.1177","volume":"7","author":[{"given":"G.","family":"Georgopoulos","sequence":"first","affiliation":[{"name":"Department of Glaucoma, University Eye Clinic of Athens, Athens - Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Andreanos","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, University Eye Clinic of Athens, Athens - Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Liokis","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, 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