{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:21:55Z","timestamp":1777580515204,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1998,1,1]],"date-time":"1998-01-01T00:00:00Z","timestamp":883612800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[1998,1]]},"abstract":"\n Background<\/jats:title>\n The purpose of the study was to determine the impact of slime-producing strains of coagulase-negative staphylococci (CNS) on non-ulcerative blepharitis. Formerly considered harmless organisms, CNS are now recognised as opportunistic pathogens. Although these microorganisms are a component of normal conjunctival flora, they often produce the typical signs and symptoms of chronic staphylococcal blepharoconjunctivitis. Certain strains produce a polysaccharide extracellular material called \u201cslime\u201d. Slime production is considered to be associated with the virulence of the organism.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Swabs were taken from the lids of 38 eyes of 19 patients with chronic non-ulcerative blepharitis and cultured for CNS. A group of 42 normal control eyes were similarly sampled. The strains of CNS isolated from 26 eyes (68.4%) of the patients with blepharitis and 25 eyes (59.5%) of the normal subjects were studied for slime layer production.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n No significant difference was found between normal subjects and patients in the incidence of slime producing CNS strains from the conjunctiva. The antibiotic sensitivity profiles of the slime-producing strains were no different from the slime-negative isolates in the blepharitis (p=0.85) and normal group (p=0.25).<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Our data suggest that slime production by CNS does not play a significant role in the pathogenesis of staphylococcal blepharitis.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/112067219800800101","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T11:16:23Z","timestamp":1523877383000},"page":"1-3","source":"Crossref","is-referenced-by-count":6,"title":["Slime Production by Coagulase-Negative Staphylococci Isolated in Chronic Blepharitis"],"prefix":"10.1177","volume":"8","author":[{"given":"S.","family":"Oto","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Baskent University, Medical School, Ankara - Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Aydin","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Baskent University, Medical School, Ankara - Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"\u00c7ift\u00e7io\u011flu","sequence":"additional","affiliation":[{"name":"Department of Microbiology, University of Kuopio, Kuopio - Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Dursun","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Baskent University, Medical School, Ankara - Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1998,1,1]]},"reference":[{"key":"bibr1-112067219800800101","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-199110010-00010"},{"key":"bibr2-112067219800800101","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6257(96)80064-6"},{"key":"bibr3-112067219800800101","first-page":"314","volume":"105","author":"McCulley J.P.","year":"1986","journal-title":"Trans Ophthalmol Soc UK"},{"key":"bibr4-112067219800800101","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.69.8.604"},{"key":"bibr5-112067219800800101","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(84)90241-1"},{"key":"bibr6-112067219800800101","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.73.6.402"},{"key":"bibr7-112067219800800101","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/161.6.1153"},{"key":"bibr8-112067219800800101","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)81593-8"},{"key":"bibr9-112067219800800101","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.37.1.318-326.1982"},{"key":"bibr10-112067219800800101","first-page":"32","volume":"105","author":"Seal D.V.","year":"1986","journal-title":"Trans Ophthalmol Soc UK"},{"key":"bibr11-112067219800800101","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1973.01000040188004"},{"key":"bibr12-112067219800800101","first-page":"751","volume":"20","author":"Cagle G.D.","year":"1981","journal-title":"Ophthalmol Vis Sci"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/112067219800800101","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/112067219800800101","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:42:45Z","timestamp":1777405365000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/112067219800800101"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,1]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1998,1]]}},"alternative-id":["10.1177\/112067219800800101"],"URL":"https:\/\/doi.org\/10.1177\/112067219800800101","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,1]]}}}