{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T19:56:37Z","timestamp":1793649397675,"version":"4.5.1"},"reference-count":18,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1998,1,1]],"date-time":"1998-01-01T00:00:00Z","timestamp":883612800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[1998,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To compare the ocular toxicity caused by the use of highly purified silicone oil to less purified silicone oil in humans.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Fifty-six eyes received 2,000 centistokes (cs) purified silicone oil (group 1) and 42 eyes received 2,000 cs fractionated (highly purified) silicone oil (group 2) after pars plana vitrectormy. Follow-up ranged from 6 to 48 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Six months after injection, the following complications were found in groups 1 and 2, respectively: ocular hypotension (&lt;13mmHg), 39.3% and 31%, sustained ocular hypertension (&gt;23mmHg), 19.6% and 19%; acute hypertensive peaks (&gt;30mmHg), 23.2% and 11.9%; corneal alterations, 19.6% and 14.3%; emulsification, 1.8% and 2.4%; silicone oil cloudiness, 28.6% and 0%; preretinal reproliferation, 14.3% and 4.8% and total or partial retinal reattachment, 78.6% and 90.5%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Highly purified silicone oil was better tolerated than the less purified oil and caused fewer complications. Poorly purified silicone oils should be avoided in clinical practice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/112067219800800311","type":"journal-article","created":{"date-parts":[[2018,3,13]],"date-time":"2018-03-13T05:16:40Z","timestamp":1520918200000},"page":"179-183","source":"Crossref","is-referenced-by-count":23,"title":["Clinical Consequences of the Use of Highly Purified Silicone Oil: Comparative study of highly and less purified silicone oil"],"prefix":"10.1177","volume":"8","author":[{"given":"J. C.","family":"Pastor","sequence":"first","affiliation":[{"name":"Vitreoretina Unit and Instituto de Oftalmobiologia Aplicada (IOBA), Universidad de Valladolid, Valladolid - Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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