{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T15:24:16Z","timestamp":1782833056556,"version":"3.54.5"},"reference-count":30,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2006,4,1]],"date-time":"2006-04-01T00:00:00Z","timestamp":1143849600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Vasc Access"],"published-print":{"date-parts":[[2006,4]]},"abstract":"<jats:p>Thrombosis of arteriovenous fistula (AVF) is the leading cause of vascular access (VA) loss usually due to silent stenosis. Therefore, assessment of relevant risk factors of VA monitoring may provide insight into potential therapeutic targets for stenosis and thrombosis. The aim of this study was to evaluate the influence of cardiovascular risk factors (including inflammation and mineral metabolism dysfunctions) on the failure of internal AVF in HD patients.<\/jats:p>\n                  <jats:p>128 HD patients with internal AVF were included in the study and followed up for two years. At baseline, VA morphology and function were followed by Doppler ultrasonography and serum albumin, prealbumine, C-reactive protein, orosomucoid, calcium, phosphorus, parathyroid hormone, bone-type alkaline phosphatase, osteoprotegerin and receptor activator of nuclear factor \u03baB ligand were measured.<\/jats:p>\n                  <jats:p>\n                    At baseline, 50 stenoses were detected but none of them required any intervention. Age and biological parameters did not significantly differ between patients with or without VA stenosis. Over the two year- follow up, VA thrombosis occurred in 19 patients. Preexisting stenosis of VA was present in 9\/19 patients (47.3% of cases) (chi-square = 3.708, p = 0.0538). Despite the low rate of events, phosphorus [1.75 (0.95\u20132.77) vs 1.42 (0.47\u20133.22) mmol\/L, p = 0.0416], Calcium x Phosphorus product [4.00 (2.00\u20135.90) vs 3.40 (1.10\u20136.80) mmol\n                    <jats:sup>2<\/jats:sup>\n                    \/L\n                    <jats:sup>2<\/jats:sup>\n                    , p = 0.0676] and parathyroid hormone [165.00 (1.00\u2013944.00) vs 79.50 (1.00\u2013846.60) ng\/L, p = 0.0814) levels were higher in the 19 thrombotic patients whereas all other biological parameters did not significantly differ.\n                  <\/jats:p>\n                  <jats:p>These results, which confirm that VA thrombosis occurs more frequently upon preexisting stenosis, also demonstrate that mineral metabolism disorders, compared to inflammation, may contribute to VA dysfunction leading to thrombosis.<\/jats:p>","DOI":"10.1177\/112972980600700207","type":"journal-article","created":{"date-parts":[[2018,1,16]],"date-time":"2018-01-16T00:47:53Z","timestamp":1516063673000},"page":"77-82","source":"Crossref","is-referenced-by-count":16,"title":["The role of mineral metabolism and inflammation on dialysis vascular access failure"],"prefix":"10.1177","volume":"7","author":[{"given":"M.","family":"Morena","sequence":"first","affiliation":[{"name":"Biochemistry Laboratory, Lapeyronie University Hospital, Montpellier - France"},{"name":"Renal Research and Training Institute, Montpellier - France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.Y.","family":"Bosc","sequence":"additional","affiliation":[{"name":"AIDER, Montpellier - France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Jaussent","sequence":"additional","affiliation":[{"name":"French National Institute of Health and Medical Research, Inserm E 0361, Montpellier - France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.M.","family":"Dupuy","sequence":"additional","affiliation":[{"name":"Biochemistry Laboratory, Lapeyronie University Hospital, Montpellier - France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Terrier","sequence":"additional","affiliation":[{"name":"Biochemistry Laboratory, Lapeyronie University Hospital, Montpellier - France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Leray-Moragues","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Lapeyronie University Hospital, Montpellier - France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.L.","family":"Flavier","sequence":"additional","affiliation":[{"name":"AIDER, Montpellier - France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Maurice","sequence":"additional","affiliation":[{"name":"Centre Hemodialyse Languedoc M\u00e9diterran\u00e9e, Montpellier - France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Delcourt","sequence":"additional","affiliation":[{"name":"French National Institute of Health and Medical Research, Inserm U593, Bordeaux - France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.P.","family":"Cristol","sequence":"additional","affiliation":[{"name":"Biochemistry Laboratory, Lapeyronie University Hospital, Montpellier - France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Canaud","sequence":"additional","affiliation":[{"name":"Renal Research and Training Institute, Montpellier - France"},{"name":"Department of Nephrology, Lapeyronie University Hospital, Montpellier - France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2006,4,1]]},"reference":[{"key":"bibr1-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V74523"},{"key":"bibr2-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfg483"},{"key":"bibr3-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1996.167"},{"key":"bibr4-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfg504"},{"key":"bibr5-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1016\/S1073-4449(12)80044-6"},{"key":"bibr6-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.80.6.1726"},{"key":"bibr7-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2001.00750.x"},{"key":"bibr8-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.13.4.609"},{"key":"bibr9-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1038\/362801a0"},{"key":"bibr10-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1997.233"},{"key":"bibr11-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1001\/jama.290.3.353"},{"key":"bibr12-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.61.s80.20.x"},{"key":"bibr13-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.1999.00575.x"},{"key":"bibr14-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2003.00864.x"},{"key":"bibr15-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1097\/00013644-200109000-00003"},{"key":"bibr16-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(03)00786-8"},{"key":"bibr17-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1177\/112972980400500203"},{"key":"bibr18-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2003.00070.x"},{"key":"bibr19-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.2001.26104"},{"key":"bibr20-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1177\/112972980100200107"},{"key":"bibr21-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)65675-1"},{"key":"bibr22-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2003.00120.x"},{"key":"bibr23-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfg414"},{"key":"bibr24-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80209-3"},{"key":"bibr25-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81569-X"},{"key":"bibr26-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000127957.43874.BB"},{"key":"bibr27-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8651(03)00079-1"},{"key":"bibr28-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(03)00675-9"},{"key":"bibr29-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.1999.00422.x"},{"key":"bibr30-112972980600700207","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/14.1.137"}],"container-title":["The Journal of Vascular Access"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/112972980600700207","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/112972980600700207","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T03:09:46Z","timestamp":1777691386000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/112972980600700207"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,4]]}},"alternative-id":["10.1177\/112972980600700207"],"URL":"https:\/\/doi.org\/10.1177\/112972980600700207","relation":{},"ISSN":["1129-7298","1724-6032"],"issn-type":[{"value":"1129-7298","type":"print"},{"value":"1724-6032","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,4]]}}}