{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:09:09Z","timestamp":1777936149613,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2022,5,23]],"date-time":"2022-05-23T00:00:00Z","timestamp":1653264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Vasc Access"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Over the past decades, significant efforts have been made to reduce early and late catheter-related complications in critically ill patients, using approaches based on bundles of evidence-based interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>In this prospective clinical study, the authors evaluated the incidence of catheter-related complications in their neuro-intensive care unit during a 4-year period, adopting systematically the GAVeCeLT bundles for the insertion and management of all central venous access devices: centrally inserted central catheters (CICCs), peripherally inserted central catheters (PICCs) and femorally inserted central catheters (FICCs). All early\/immediate and late complications were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>On 486 central lines (328 CICCs, 149 PICCs and 9 FICCs), the only clinically relevant early\/immediate complication was primary tip malposition (1%). In regards late infective complications, the authors did not record any case of catheter-related bloodstream infection; though, they observed one case of central line associated blood stream infection (one CICC; 0.14\/1000 catheter days), and 15 cases of catheter colonization (12 CICCs and 3 PICCs; 2.09 episodes\/1000 catheter days). Late non-infective complications were few: 14 accidental dislodgments (2.9%), 18 irreversible lumen occlusions (3.7%), and no episodes of symptomatic catheter-related thrombosis or tip migration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The systematic adoption of the GAVeCeLT bundles for CVAD insertion and maintenance was associated with a minimization of catheter-related complications. The strict adherence to the recommendations included in these bundles was the major determinant for clinical success.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11297298221097267","type":"journal-article","created":{"date-parts":[[2022,5,23]],"date-time":"2022-05-23T04:19:11Z","timestamp":1653279551000},"page":"100-106","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Prospective clinical study on the incidence of catheter-related complications in a neurological intensive care unit: 4\u2009years of experience"],"prefix":"10.1177","volume":"25","author":[{"given":"Denise","family":"Bolis","sequence":"first","affiliation":[{"name":"Department of Neurosciences, Ospedale Alessandro Manzoni-ASST, Lecco, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6740-3195","authenticated-orcid":false,"given":"Sonia","family":"D\u2019Arrigo","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Intensive Care, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Universit\u00e0 Cattolica del Sacro Cuore, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Bartesaghi","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Ospedale Alessandro Manzoni-ASST, Lecco, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Panzeri","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Ospedale Alessandro Manzoni-ASST, Lecco, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Pelegalli","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Ospedale Alessandro Manzoni-ASST, Lecco, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Steffanoni","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Ospedale Alessandro Manzoni-ASST, Lecco, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giancarlo","family":"Scoppettuolo","sequence":"additional","affiliation":[{"name":"Department of Infective Diseases, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Universit\u00e0 Cattolica del Sacro Cuore, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2225-7654","authenticated-orcid":false,"given":"Mauro","family":"Pittiruti","sequence":"additional","affiliation":[{"name":"Department of Surgery, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Universit\u00e0 Cattolica del Sacro Cuore, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,5,23]]},"reference":[{"key":"bibr1-11297298221097267","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-021-06506-y"},{"key":"bibr2-11297298221097267","doi-asserted-by":"publisher","DOI":"10.1086\/599376"},{"key":"bibr3-11297298221097267","doi-asserted-by":"publisher","DOI":"10.1016\/j.medin.2017.09.012"},{"key":"bibr4-11297298221097267","doi-asserted-by":"publisher","DOI":"10.1016\/j.idh.2019.03.001"},{"key":"bibr5-11297298221097267","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2019.02.004"},{"key":"bibr6-11297298221097267","doi-asserted-by":"publisher","DOI":"10.1097\/NAN.0000000000000396"},{"key":"bibr7-11297298221097267","unstructured":"Pittiruti M, Scoppettuolo G. 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