{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:10:18Z","timestamp":1777936218713,"version":"3.51.4"},"reference-count":36,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T00:00:00Z","timestamp":1698105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Vasc Access"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Pleural mesothelioma (PM) is a rare and aggressive cancer. PICC devices are widely used in cancer patients. The aim of the study is to evaluate the quality of life of patients with PICC diagnosed with PM treated at the Hospital of Casale Monferrato and Alessandria (Italy), an area with a high incidence of asbestos-related diseases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study design and methods:<\/jats:title>\n                    <jats:p>Longitudinal prospective observational study with data collection at PICC insertion (T0), after 3\u2009months (T1), 6\u2009months (T2), and 9\u2009months (T3). Participants were aged &gt;18\u2009years, diagnosed with PM, eligible for PICC insertion. Questionnaires used: EORTC QLQ-C30, EORTC QLQ-LC13, and HADS rating scale.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Twenty-eight patients were enrolled. The mean age was 68.93\u2009years (SD 9.13), mostly male (57.1%). The most frequent cancer stage at diagnosis was III (39.3%), then I (32.1%), and IV (21.4%). 85.7% were treated with chemotherapy, 14.3% also with immunotherapy. 96.4% of patients reported no complications during PICC implantation. The perception of health status and quality of life, measured on a scale of 1\u20137, was in line with an average score of 5 during the evaluation period. The total anxiety and depression score remained normal for most patients (0\u20137).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The PICC management involved a multidisciplinary team with different skills: study findings revealed the key role that dedicated nurses play in PICC placement and ensuring patient problems are promptly addressed. From our study results, PICC placement does not seem to negatively impact the patient\u2019s quality of life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11297298231202046","type":"journal-article","created":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T07:40:12Z","timestamp":1698133212000},"page":"217-227","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Quality of life in patients with PICC diagnosed with mesothelioma: Results of a multicenter epidemiological survey (LifePICC)"],"prefix":"10.1177","volume":"26","author":[{"given":"Tatiana","family":"Bolgeo","sequence":"first","affiliation":[{"name":"Research Training Innovation Infrastructure, Research and Innovation Department (DAIRI), Azienda Ospedaliera \u201cSS. 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Antonio e Biagio e Cesare Arrigo,\u201d Alessandria, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonina","family":"De Angelis","sequence":"additional","affiliation":[{"name":"Mesothelioma and Rare Tumors Unit, Azienda Ospedaliera \u201cSS. Antonio e Biagio e Cesare Arrigo,\u201d Alessandria, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Delfanti","sequence":"additional","affiliation":[{"name":"Mesothelioma and Rare Tumors Unit, Azienda Ospedaliera \u201cSS. Antonio e Biagio e Cesare Arrigo,\u201d Alessandria, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabetta","family":"Ferrero","sequence":"additional","affiliation":[{"name":"Oncology and Hematology Day Hospital, Azienda Ospedaliera \u201cSS. 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