{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T23:33:14Z","timestamp":1788564794940,"version":"build-2803163510"},"reference-count":31,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T00:00:00Z","timestamp":1762819200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T00:00:00Z","timestamp":1762819200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100018703","name":"HORIZON EUROPE European Innovation Council","doi-asserted-by":"publisher","award":["EIC Accelerator grant 96196"],"award-info":[{"award-number":["EIC Accelerator grant 96196"]}],"id":[{"id":"10.13039\/100018703","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Vasc Access"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Placement of a short peripheral catheter (SPC) is one of the most common invasive procedures in healthcare. Catheter dysfunction occurs in up to 69%, caused by phlebitis, subcutaneous infiltration, occlusion, and dislodgement, conjointly considered as mechanical complications. Recent research has indicated that a new type of medical device, the force-activated separation device (FASD), may reduce these mechanical complications by 46%, but efficacy and safety data are lacking. The objective of this study was to investigate the efficacy and rate of adverse events (AEs) using a novel FASD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>This was a single center randomized controlled trial comparing a FASD to standard of care, where primary outcome was rate of mechanical complications for each arm. Adult patients, admitted to either a stroke ward or orthopedic ward at a University Hospital were eligible.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The population was mainly male, elderly, and had multiple co-morbidities. The study included 146 patients, contributing with a total of 194 catheters for the per protocol (PP) and 203 for the intention to treat (ITT) analyses. In the PP analysis, the total mechanical complication rate was 42% versus 46% (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.56), while the dislodgement rate was 3.4% versus 12% (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.04) in the intervention and control group, respectively. For ITT, total mechanical complication rate was 42% versus 47% (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.47) and the dislodgement rate was 4.2% versus 13% (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.03) in the intervention and control groups. FASD implementation resulted in a 73% reduction in dislodgements in the PP, and a 68% reduction in the ITT analysis. No device related AEs were recorded.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The implementation of a novel FASD did not demonstrate a reduction of total mechanical complications, however, a 73% reduction in dislodgements in the PP, and a 68% reduction in the ITT analysis was noted. No device-related AEs were recorded.<\/jats:p>\n                    <jats:p>Clinical Trials; clinicaltrials.gov; ID: NCT05814887.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11297298251389658","type":"journal-article","created":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T11:10:18Z","timestamp":1762859418000},"page":"1179-1188","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["The effects of a new device on mechanical complications of short peripheral intravenous catheters: A randomized controlled trial"],"prefix":"10.1177","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7922-5875","authenticated-orcid":false,"given":"Christopher","family":"Blacker","sequence":"first","affiliation":[{"name":"Department of Women\u2019s and Children\u2019s Health, Uppsala University, Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5547-5626","authenticated-orcid":false,"given":"Ali-Reza","family":"Modiri","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences, Section of Anaesthesia and Intensive Care Medicine, Uppsala University, Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4949-2494","authenticated-orcid":false,"given":"Gustaf","family":"Ljungman","sequence":"additional","affiliation":[{"name":"Department of Women\u2019s and Children\u2019s Health, Uppsala University, Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6402-136X","authenticated-orcid":false,"given":"Peter","family":"Frykholm","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences, Section of Anaesthesia and Intensive Care Medicine, Uppsala University, Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,11,11]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.12788\/jhm.3039"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2023.104673"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/NAN.0000000000000100"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61082-4"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/11297298211015035"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2021.104095"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(21)00206-4"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1177\/1129729820974259"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2010.19.21.79998"},{"key":"e_1_3_3_11_2","article-title":"Clinically-indicated replacement versus routine replacement of peripheral venous catheters","volume":"1","author":"Webster J","year":"2019","unstructured":"Webster J, Osborne S, Rickard CM, et al. 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