{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T07:06:54Z","timestamp":1784531214944,"version":"3.55.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T00:00:00Z","timestamp":1768521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Sichuan Cancer Hospital nursing research specialized funding","award":["HL202401"],"award-info":[{"award-number":["HL202401"]}]},{"name":"Sichuan Nursing Association Scientific Research Project","award":["PlanH23054"],"award-info":[{"award-number":["PlanH23054"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Vasc Access"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To test the optimum flushing volume for power-injectable peripherally inserted central catheters after the injection of iodinated contrast agents.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Pulsed infusion with saline solution was recommended for peripherally inserted central catheters flushing. However, evidence of flushing volume for power-injectable peripherally inserted central catheters after the injection of iodinated contrast agent was lacking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Empirical quantitative research in vitro experiment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Single lumen power-injectable peripherally inserted central catheters were filled with an iodinated contrast agent. Sixty catheters were randomized into four groups: 10\u2009ml flushing volume of 0.9% sodium chloride (Group A), 15\u2009ml flushing volume of normal saline (Group B), 20\u2009ml flushing volume of 0.9% sodium chloride (Group C), and 25\u2009ml flushing volume of 0.9% sodium chloride (Group D). The same pulsatile flushing technique was performed for all four groups. Efficacy was measured based on the amount of iodine recovered from the lumen of the tested catheters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The iodine average recovery proportion was 98.5%\u2009\u00b1\u20092.1% in Group A, 99.3%\u2009\u00b1\u20091.4% in Group B, 98.4%\u2009\u00b1\u20091.8% in Group C, and 97.2%\u2009\u00b1\u20093.2% in Group D. The difference in proportion of iodine recovery between the control group (Group A) and the three experimental groups (Groups B, C, and D) was not significant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>We concluded that pulsed flushing with 10\u2009ml normal saline immediately after the contrast agent injection was sufficient. Higher flushing volumes did not lead to a better flushing effect; rather, they would only bring unnecessary fluid burden and cost to patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patient or public contribution:<\/jats:title>\n                    <jats:p>No patient or public contribution.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11297298251409608","type":"journal-article","created":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T12:25:31Z","timestamp":1768566331000},"page":"1598-1602","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Flushing efficacy of high concentration iodinated contrast agent in power-injectable peripherally inserted central catheters: Evaluating different flush volumes in vitro"],"prefix":"10.1177","volume":"27","author":[{"given":"Ling","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Radiology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital &amp; Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Nursing, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital &amp; Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital &amp; Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongzhu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital &amp; Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Nursing, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital &amp; Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-0929-3618","authenticated-orcid":false,"given":"Haomiao","family":"Qing","sequence":"additional","affiliation":[{"name":"Department of Radiology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital &amp; Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,1,16]]},"reference":[{"issue":"21","key":"e_1_3_3_2_2","first-page":"3540","article-title":"Application of PowerPICC in intravenous therapy of tumor patients","volume":"38","author":"Huang X","year":"2019","unstructured":"Huang X, Xiu M, Jiang H. 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