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This paper describes an insertion bundle\u2014developed by the Italian Group of Long-Term Venous Access Devices (GAVeCeLT) and by the Italian Vascular Access Society (IVAS), and named \u201cSIMiC\u201d (Safe Insertion of Midline Catheters)\u2014consisting of a few evidence-based strategies aimed at reducing all immediate, early, or late complications potentially associated with the insertion of MCs. The SIMiC bundle includes seven steps: (1) systematic ultrasound evaluation of the veins of the arms and the supra\/infra-clavicular area; (2) choice of the most appropriate vein of the upper arm; (3) appropriate hand hygiene, proper skin antisepsis, and maximal barrier precautions; (4) ultrasound-guided venipuncture; (5) intra-procedural tip location, using infra\/supraclavicular ultrasound scan; (6) sutureless securement, preferably using subcutaneous anchorage; (7) protection of the exit site with cyanoacrylate glue and semipermeable transparent membrane.<\/jats:p>","DOI":"10.1177\/11297298261445794","type":"journal-article","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T06:11:32Z","timestamp":1779343892000},"page":"2010-2017","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["A GAVeCeLT-IVAS bundle for the Safe Insertion of Midline Catheters: The SIMiC 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