{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:35:33Z","timestamp":1792787733826,"version":"4.5.0"},"reference-count":21,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100004587","name":"instituto de salud carlos iii","doi-asserted-by":"publisher","award":["RICORS 2040 RD24\/0004\/0027"],"award-info":[{"award-number":["RICORS 2040 RD24\/0004\/0027"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"name":"CERCA Programme\/Generalitat de Catalunya","id":[{"id":"https:\/\/ror.org\/01bg62x04","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Vasc Access"],"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Primary maturation failure (PMF) remains a major limitation of autologous arteriovenous fistulas (AVFs) for hemodialysis and may increase long-term catheter dependence. We aimed to identify predictors of PMF and evaluate its association with survival outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We conducted a retrospective single-center cohort study including adult patients undergoing first AVF creation between 2016 and 2020. PMF was defined as failure to achieve a functional AVF suitable for hemodialysis within 3\u2009months according to clinical and Doppler ultrasound criteria. Predictors of PMF were analyzed using multivariable logistic regression. Overall survival was evaluated using Kaplan-Meier analysis and Cox proportional hazards models with follow-up truncated at 4\u2009years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 413 patients were included; PMF occurred in 124 cases (30.0%). Patients with PMF had smaller preoperative vein diameter (2.68\u2009\u00b1\u20090.49 vs. 4.02\u2009\u00b1\u20093.56\u2009mm;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and a higher proportion of distal AVFs (43.1% vs. 23.9%;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001). In multivariable analysis, preoperative vein diameter was the only independent predictor of PMF (OR 0.13, 95% CI 0.07\u20130.25;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001). During follow-up, 113 patients died. Overall survival did not differ between patients with and without PMF (log-rank\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.938), and PMF was not independently associated with mortality after adjustment. However, among patients with PMF, prolonged catheter exposure was independently associated with increased mortality (HR 3.29, 95% CI 1.64\u20136.59;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>PMF was primarily associated with preoperative venous anatomy and was not independently associated with mortality. However, persistent catheter dependence after PMF identified a high-risk subgroup with increased mortality. These findings highlight the importance of careful preoperative vascular assessment, continued prioritization of AVF creation, and strategies aimed at minimizing prolonged catheter exposure after initial maturation failure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11297298261489661","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:52:26Z","timestamp":1790747546000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Primary maturation failure of arteriovenous fistulas for hemodialysis: Risk factors and impact on survival"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7722-1173","authenticated-orcid":false,"given":"Diego","family":"Sandoval Rodr\u00edguez","sequence":"first","affiliation":[{"name":"Department of Nephrology, Hospital Universitari Bellvitge, L\u2019Hospitalet de Llobregat, Spain"},{"name":"Bellvitge Biomedical Research Institute (IDIBELL), L\u2019Hospitalet de Llobregat, Spain"},{"name":"Doctoral Programme in Medicine and Translational Research, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bego\u00f1a","family":"Gonzalo","sequence":"additional","affiliation":[{"name":"Bellvitge Biomedical Research Institute (IDIBELL), L\u2019Hospitalet de Llobregat, Spain"},{"name":"Department of Vascular Surgery, Hospital Universitari Bellvitge, L\u2019Hospitalet de Llobregat, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Espinar","sequence":"additional","affiliation":[{"name":"Bellvitge Biomedical Research Institute (IDIBELL), L\u2019Hospitalet de Llobregat, Spain"},{"name":"Department of Vascular Surgery, Hospital Universitari Bellvitge, L\u2019Hospitalet de Llobregat, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9063-4602","authenticated-orcid":false,"given":"Silo\u00e9","family":"Palacios","sequence":"additional","affiliation":[{"name":"Bellvitge Biomedical Research Institute (IDIBELL), L\u2019Hospitalet de Llobregat, Spain"},{"name":"Department of Vascular Surgery, Hospital Universitari Bellvitge, L\u2019Hospitalet de Llobregat, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronny","family":"Rodr\u00edguez-Urqu\u00eda","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Hospital Universitari Bellvitge, L\u2019Hospitalet de Llobregat, Spain"},{"name":"Bellvitge Biomedical Research Institute (IDIBELL), L\u2019Hospitalet de Llobregat, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Alba","sequence":"additional","affiliation":[{"name":"Bellvitge Biomedical Research Institute (IDIBELL), L\u2019Hospitalet de Llobregat, Spain"},{"name":"Department of Interventional Radiology, Hospital Universitari Bellvitge, L\u2019Hospitalet de Llobregat, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Alvarez","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Hospital Universitari Bellvitge, L\u2019Hospitalet de Llobregat, Spain"},{"name":"Bellvitge Biomedical Research Institute (IDIBELL), L\u2019Hospitalet de Llobregat, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In\u00e9s","family":"Rama","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Hospital Universitari Bellvitge, L\u2019Hospitalet de Llobregat, Spain"},{"name":"Bellvitge Biomedical Research Institute (IDIBELL), L\u2019Hospitalet de Llobregat, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Hueso","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Hospital Universitari Bellvitge, L\u2019Hospitalet de Llobregat, Spain"},{"name":"Bellvitge Biomedical Research Institute (IDIBELL), L\u2019Hospitalet de Llobregat, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep M","family":"Cruzado","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Hospital Universitari Bellvitge, L\u2019Hospitalet de Llobregat, Spain"},{"name":"Bellvitge Biomedical Research Institute (IDIBELL), L\u2019Hospitalet de Llobregat, Spain"},{"name":"Department of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"Organitzaci\u00f3 Catalana de Trasplantaments. 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