{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:13:50Z","timestamp":1777936430451,"version":"3.51.4"},"reference-count":38,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["T32AI052074 to A.M., L.H., and P.S."],"award-info":[{"award-number":["T32AI052074 to A.M., L.H., and P.S."]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007161","name":"Boston University","doi-asserted-by":"publisher","award":["School of Medicine Department of Medicine Evans Ca"],"award-info":[{"award-number":["School of Medicine Department of Medicine Evans Ca"]}],"id":[{"id":"10.13039\/100007161","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["K23DA044085 to S.A.A."],"award-info":[{"award-number":["K23DA044085 to S.A.A."]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["R25DA033211 to L.H"],"award-info":[{"award-number":["R25DA033211 to L.H"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000861","name":"Burroughs Wellcome Fund","doi-asserted-by":"publisher","award":["Postdoctoral fellowship to P.S."],"award-info":[{"award-number":["Postdoctoral fellowship to P.S."]}],"id":[{"id":"10.13039\/100000861","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Subst\ufffdAbuse"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>People with substance use disorders (SUD) are suggested to have higher risk of hospitalization, intubation, or death from coronavirus disease 2019 (COVID-19), although data are mixed. Little is known about other COVID-19-related complications in this group. We compared morbidity and mortality among individuals with and without SUD who were admitted to an urban safety net hospital with COVID-19 early in the pandemic, contemporaneous to other published studies on this subject.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We performed a retrospective study of patients \u2a7e18\u2009years old admitted with COVID-19 from March 16th to April 8th, 2020. SUD included alcohol, opioid, cocaine, amphetamine, and benzodiazepine use disorders and was identified using diagnostic codes, free text clinical documentation, and urine drug screens. The primary outcome was inpatient mortality. Secondary outcomes included clinical complications (eg, secondary infections, venous thromboembolism) and resource utilization (eg, mechanical ventilation, length of stay). We used multivariable regression to assess the relationship between SUD and mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Of 409 patients, the mean age was 56\u2009years and 13.7% had SUD. Those with SUD were more likely to be male, have experienced homelessness, have pulmonary disease or hepatitis C, or use tobacco or cannabis. After multivariable analysis, SUD was not associated with mortality (aOR 1.03; 95% CI, 0.31-3.10). Secondary outcomes were also similar between groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Our findings suggest that persons with and without SUD have similar COVID-19-related outcomes. Previously reported increased COVID-19 complications may be from medical comorbidities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11782218231160014","type":"journal-article","created":{"date-parts":[[2023,3,22]],"date-time":"2023-03-22T06:22:31Z","timestamp":1679466151000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Comparing COVID-19-related Morbidity and Mortality Between Patients With and Without Substance Use Disorders: A Retrospective Cohort Study"],"prefix":"10.1177","volume":"17","author":[{"given":"Angela","family":"McLaughlin","sequence":"first","affiliation":[{"name":"Section of Infectious Diseases, Department of Medicine, Boston Medical Center, Boston, MA, USA"},{"name":"Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"Burns","sequence":"additional","affiliation":[{"name":"Internal Medicine Residency Program, Department of Medicine, Boston University School of Medicine, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morgan","family":"Ryan","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wafaa","family":"Abbasi","sequence":"additional","affiliation":[{"name":"Boston University School of Medicine, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leah","family":"Harvey","sequence":"additional","affiliation":[{"name":"Section of Infectious Diseases, Department of Medicine, Boston Medical Center, Boston, MA, USA"},{"name":"Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston, MA, USA"},{"name":"Grayken Center for Addiction, Department of Medicine, Boston University School of Medicine, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline","family":"Hicks","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pranay","family":"Sinha","sequence":"additional","affiliation":[{"name":"Section of Infectious Diseases, Department of Medicine, Boston Medical Center, Boston, MA, USA"},{"name":"Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabrina A","family":"Assoumou","sequence":"additional","affiliation":[{"name":"Section of Infectious Diseases, Department of Medicine, Boston Medical Center, Boston, MA, USA"},{"name":"Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,3,22]]},"reference":[{"key":"bibr1-11782218231160014","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2006.10.014"},{"key":"bibr2-11782218231160014","first-page":"133","volume":"11","author":"Farhoudian A","year":"2020","journal-title":"Basic Clin Neurosci"},{"key":"bibr3-11782218231160014","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0075133"},{"key":"bibr4-11782218231160014","doi-asserted-by":"publisher","DOI":"10.1097\/YCO.0000000000000711"},{"key":"bibr5-11782218231160014","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.18543"},{"key":"bibr6-11782218231160014","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(20)30251-X"},{"key":"bibr7-11782218231160014","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.202000534"},{"key":"bibr8-11782218231160014","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-020-00895-0"},{"key":"bibr9-11782218231160014","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyaa140"},{"key":"bibr10-11782218231160014","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2021.100938"},{"key":"bibr11-11782218231160014","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2022.109383"},{"key":"bibr12-11782218231160014","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.13031"},{"key":"bibr13-11782218231160014","doi-asserted-by":"publisher","DOI":"10.1093\/pubmed\/fdaa241"},{"key":"bibr14-11782218231160014","unstructured":"Centers for Disease Control and Prevention. 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