{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T22:18:14Z","timestamp":1788905894034,"version":"build-2803163510"},"reference-count":16,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Environ\ufffdHealth\ufffdInsights"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Candida is one of the common pathogens in nosocomial infections. Culture is the gold standard for diagnosing candidemia. Candida albicans is identified via the germ tube test, which uses serum as the culture medium, which is costly and time-consuming. This study was conducted to evaluate and compare a relatively simple, fast, and reliable method for the detection of Candida albicans.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We conducted this randomized case study at Taipei City Hospital (TCH) from January 2023 to August 2023, with a total of 30 specimen culture reports collected and confirmed to be cases of Candida albicans infection. A germ tube test was performed in a 37\u00b0C water bath using serum, plasma, and safe plasma products (Fresh Frozen Plasma, FFP). Further, the same procedures were repeated with the addition of 22% bovine serum albumin (BSA) to the identification\/culture.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>By adding BSA, more than 50% of the budding phenomenon was observed in 40\u2009minutes, which shortened the diagnosis time compared with the traditional method (2-3\u2009hours). Using BSA can shorten the identification time for early clinical medication and improve the quality of medical care<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Using safer plasma products for germ tube test of candidiasis not only reduced the risk of infection for medical technicians but could also replace the serum used in traditional methods to increase convenience and save time. This study proposed BSA as a germ tube induction medium enhancer, which reduced the culture time, thereby enabling quicker diagnosis of C. albicans infections.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11786302241272398","type":"journal-article","created":{"date-parts":[[2024,9,14]],"date-time":"2024-09-14T10:13:55Z","timestamp":1726308835000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["A Simple, Fast, and Reliable Method for the Identification of\n                    <i>Candida albicans<\/i>"],"prefix":"10.1177","volume":"18","author":[{"given":"Su Jane Fan","family":"Chiang","sequence":"first","affiliation":[{"name":"Department of Clinical Laboratory, Zhongxiao Branch, Taipei City Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei-Kuei","family":"Chien","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Zhongxiao Branch, Taipei City Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Yi","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Zhongxiao Branch, Taipei City Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jui-Chang","family":"Hsiao","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Zhongxiao Branch, Taipei City Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan-Hlan","family":"Koo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics\/Gynaecology, Taipei City Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yung-Feng","family":"Yen","sequence":"additional","affiliation":[{"name":"Section of Infectious Diseases, Taipei City Hospital, Yangming Branch, Taipei, Taiwan"},{"name":"Institute of Public Health, National Yang Ming Chiao Tung University, Taipei, Taiwan"},{"name":"Department of Health Care Management, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan"},{"name":"Institute of Public Health, National Yang Ming Chiao Tung University, Taipei, Taiwan"},{"name":"University of Taipei, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Chang","family":"Chou","sequence":"additional","affiliation":[{"name":"University of Taipei, Taipei, Taiwan"},{"name":"Department of Education and Research, Taipei City Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1645-8457","authenticated-orcid":false,"given":"Chih-Chien","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Obstetrics\/Gynaecology, Taipei City Hospital, Taipei, Taiwan"},{"name":"University of Taipei, Taipei, Taiwan"},{"name":"Department of Education and Research, Taipei City Hospital, Taipei, Taiwan"},{"name":"School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,9,14]]},"reference":[{"key":"bibr1-11786302241272398","doi-asserted-by":"publisher","DOI":"10.1086\/596757"},{"key":"bibr2-11786302241272398","first-page":"1","volume":"54","author":"Pfaller MA","year":"2016","journal-title":"Med Mycol"},{"key":"bibr3-11786302241272398","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2018.09.014"},{"key":"bibr4-11786302241272398","first-page":"98","author":"Rodrigues 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