{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T12:03:24Z","timestamp":1780747404226,"version":"3.54.1"},"reference-count":108,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"University of Ghana Medical School","award":["D43TW012487"],"award-info":[{"award-number":["D43TW012487"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Environ\ufffdHealth\ufffdInsights"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:p>\n                    <jats:italic toggle=\"yes\">Enterococcus<\/jats:italic>\n                    species are part of normal microbiota but can cause severe infections, especially among hospital-adapted strains. In Ghana, data on their dynamics, including prevalence and resistance patterns, remain limited. This systematic review and meta-analysis is the first to assess the current scope and identify gaps in One-Health research on\n                    <jats:italic toggle=\"yes\">Enterococcus<\/jats:italic>\n                    . We searched PubMed\/MEDLINE, Scopus, and Web of Science following PRISMA 2020 guidelines for studies published up to October 24, 2024 (search conducted October 12\u201324, 2024). A random-effects model with restricted maximum likelihood was used to pool prevalence and antimicrobial resistance. Sixty-nine studies met the inclusion criteria with nineteen eligible for meta-analysis. The pooled prevalence of\n                    <jats:italic toggle=\"yes\">Enterococcus<\/jats:italic>\n                    was 6.76% (CI: 1.19\u201316.39, I\n                    <jats:sup>2<\/jats:sup>\n                    = 99.3%, p &lt; 0.0001) while adjusted vancomycin-resistance isolates was 0.06% (CI: 0.00\u201327.86; I\n                    <jats:sup>2<\/jats:sup>\n                    = 99.4%, p &lt; 0.0001). Antibiotic resistance rates were comparable across human and animal studies, often higher in animals. Ciprofloxacin showed the lowest resistance (1.30%), while cloxacillin had the highest (17.46%). This review underscores the one-sided focus on humans, limiting understanding of transmission within the One-Health spectrum. We advocate integrating genomic approaches, particularly environmental genomics, into One-Health frameworks to resolve transmission pathways, inform policy, and strengthen antimicrobial resistance control in Ghana.\n                  <\/jats:p>","DOI":"10.1177\/11786302261455118","type":"journal-article","created":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T05:28:38Z","timestamp":1780464518000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["A One-Health Perspective on\n                    <i>Enterococcus<\/i>\n                    in Ghana: A Review and Meta-Analysis"],"prefix":"10.1177","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9775-6167","authenticated-orcid":false,"given":"Bill Clinton","family":"Aglomasa","sequence":"first","affiliation":[{"name":"Medical School, University of Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patience","family":"Sarkodie-Addo","sequence":"additional","affiliation":[{"name":"Medical School, University of Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace","family":"Semevor","sequence":"additional","affiliation":[{"name":"Medical School, University of Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5179-546X","authenticated-orcid":false,"given":"Eric Sampane","family":"Donkor","sequence":"additional","affiliation":[{"name":"Medical School, University of Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,6,2]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11274-024-04007-w"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2024.01.008"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-024-01058-6"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.idnow.2024.104940"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.7754\/Clin.Lab.2019.190941"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12088-024-01216-7"},{"key":"e_1_3_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)02724-0"},{"key":"e_1_3_6_9_2","unstructured":"World Health Organization. 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