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The analysis was conducted from a societal perspective using Excel-based modeling in hypothetical cohorts initiating screening at age 45.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Under base-case assumptions, a 10 percentage-point improvement in CRC screening attributable to the program increased LYG by 0.160 at an additional lifetime cost of $101, resulting in an ICER of $3098 per LYG. One-way and two-way sensitivity analyses were conducted, varying program costs, screening rate improvements, lifetime CRC costs, and life-years gained (LYG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Our findings underscore the importance of CHW navigation services incorporating CRC screening promotion strategies tailored to uninsured populations to alleviate disparities in colorectal cancer screening and outcomes. Further research should consider the characteristics of uninsured populations, and the applicability of the program targeted for various types of underserved populations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11786329251399778","type":"journal-article","created":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T07:00:19Z","timestamp":1765868419000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Examining the Cost-Effectiveness of Introducing Patient Navigation Services for Colorectal Cancer Screening Among a Low-Income and Uninsured Population"],"prefix":"10.1177","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0138-4213","authenticated-orcid":false,"given":"Wen Hsin","family":"Chen","sequence":"first","affiliation":[{"name":"University of Illinois Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6117-056X","authenticated-orcid":false,"given":"Robert","family":"Ohsfeldt","sequence":"additional","affiliation":[{"name":"Texas A&amp;M University, College Station, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murray","family":"C\u00f4t\u00e9","sequence":"additional","affiliation":[{"name":"Texas A&amp;M University, College Station, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Shipp","sequence":"additional","affiliation":[{"name":"Texas A&amp;M University, College Station, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marivel","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Texas A&amp;M University, College Station, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2749-2992","authenticated-orcid":false,"given":"Arica","family":"Brandford","sequence":"additional","affiliation":[{"name":"Houston Methodist, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane N.","family":"Bolin","sequence":"additional","affiliation":[{"name":"Texas A&amp;M University, College Station, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,12,15]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21772"},{"issue":"7","key":"e_1_3_4_3_2","article-title":"Obstructing Stage IV Adenocarcinoma of the transverse colon in a young patient with vitiligo","volume":"15","author":"Mueller E","year":"2023","unstructured":"Mueller E, Shaik Z, Addepalli D, Malik S, Schiefelbein P. 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