{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T13:30:15Z","timestamp":1753882215009,"version":"3.41.2"},"reference-count":21,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbiol\ufffdInsights"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec><jats:title>Objective:<\/jats:title><jats:p> The aim of this study is to assess whether choice of test for tuberculosis (TB) infection affects decisions to accept and complete treatment among contacts to TB cases. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> Retrospective study is conducted in which TB contacts, \u2a7e15\u2009years old during 2005 and 2009, were tested for infection with either a tuberculin skin test (TST) or an interferon-gamma release assay test, the QuantiFERON-TB Gold In-Tube (QFT-GIT). <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> Of 658 persons with valid test results, 185 (28%) had positive results, including 128 of 406 (32%) who had TST and 57 of 252 (23%) who received QFT-GIT. Treatment acceptance was 43 of 57 (75%) among QFT-GIT-positive and 97 of 128 (76%) among TST-positive persons (risk ratio [RR]\u2009=\u20091.0, 95% confidence interval [CI], 0.83-1.2). Treatment completion was 56% among QFT-GIT-positive (32 of 57) and 59% (75 of 128) among TST-positive persons (RR\u2009=\u20090.96, 95% CI, 0.73-1.26). <\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion:<\/jats:title><jats:p> Our study showed no difference in proportions of TB contacts \u2a7e15\u2009years old with positive TST results who accepted or completed LTBI treatment compared with those with positive QFT-GIT results. Future studies should include high-risk persons with no known TB exposure, who constitute the main reservoir for TB cases in the United States. <\/jats:p><\/jats:sec>","DOI":"10.1177\/1178636118811311","type":"journal-article","created":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T09:50:22Z","timestamp":1543312222000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Impact of Choice of Test for Latent Tuberculosis Infection on Treatment Acceptance and Completion"],"prefix":"10.1177","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6608-6319","authenticated-orcid":false,"given":"Lauren A","family":"Lambert","sequence":"first","affiliation":[{"name":"Centers for Disease Control and Prevention, Division of TB Elimination Atlanta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dolly","family":"Katz","sequence":"additional","affiliation":[{"name":"Centers for Disease Control and Prevention, Division of TB Elimination Atlanta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pei-Jean","family":"Feng","sequence":"additional","affiliation":[{"name":"Centers for Disease Control and Prevention, Division of TB Elimination Atlanta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baby M","family":"Djojonegoro","sequence":"additional","affiliation":[{"name":"Francis J. Curry National TB Center, San Francisco, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Fair","sequence":"additional","affiliation":[{"name":"Francis J. Curry National TB Center, San Francisco, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Supriya","family":"Jasuja","sequence":"additional","affiliation":[{"name":"Respiratory Health Association, Cook County Department of Public Health, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Marantz","sequence":"additional","affiliation":[{"name":"Respiratory Health Association, Cook County Department of Public Health, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"C Robert","family":"Horsburgh","sequence":"additional","affiliation":[{"name":"School of Public Health, Boston University, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Ho","sequence":"additional","affiliation":[{"name":"Centers for Disease Control and Prevention, Division of TB Elimination Atlanta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,11,27]]},"reference":[{"key":"bibr1-1178636118811311","unstructured":"Centers for Disease Control and Prevention (CDC). Targeted tuberculin testing and treatment of latent tuberculosis infection. MMWR: Morbid Mortal W. 2000;49:1-51. http:\/\/www.cdc.gov\/mmwr\/PDF\/rr\/rr4906.pdf. Accessed August 29, 2017."},{"key":"bibr2-1178636118811311","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2010.01751.x"},{"key":"bibr3-1178636118811311","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0138349"},{"key":"bibr4-1178636118811311","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-016-1550-y"},{"key":"bibr5-1178636118811311","doi-asserted-by":"publisher","DOI":"10.1378\/chest.09-0394"},{"key":"bibr6-1178636118811311","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2006.04.010"},{"key":"bibr7-1178636118811311","first-page":"1235","volume":"12","author":"Hirsch-Moverman Y","year":"2008","journal-title":"Int J Tuberc Lung Dis"},{"key":"bibr8-1178636118811311","first-page":"544","volume":"109","author":"Judson FN","year":"1974","journal-title":"Am Rev Respir Dis"},{"key":"bibr9-1178636118811311","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02742-2"},{"key":"bibr10-1178636118811311","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001012"},{"key":"bibr11-1178636118811311","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1985.03350470090027"},{"key":"bibr12-1178636118811311","unstructured":"World Health Organization. BCG: immunization coverage estimates by WHO region. http:\/\/apps.who.int\/gho\/data\/view.main.81500?lang=en.Updated2017. Accessed September 4, 2018."},{"key":"bibr13-1178636118811311","first-page":"49","volume":"54","author":"Centers for Disease Control and Prevention (CDC)","year":"2005","journal-title":"MMWR: Morbid Mortal W"},{"key":"bibr14-1178636118811311","doi-asserted-by":"publisher","DOI":"10.1016\/j.tube.2005.12.003"},{"key":"bibr15-1178636118811311","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa031667"},{"key":"bibr16-1178636118811311","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00214014"},{"key":"bibr17-1178636118811311","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01546-2016"},{"key":"bibr18-1178636118811311","doi-asserted-by":"publisher","DOI":"10.1353\/hpu.2015.0126"},{"key":"bibr19-1178636118811311","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix505"},{"key":"bibr20-1178636118811311","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-017-2377-x"},{"key":"bibr21-1178636118811311","unstructured":"Centers for Disease Control and Prevention (CDC). Reported Tuberculosis in the United States, 2016. 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