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This review was conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Relevant data were extracted, and R language 4.2.0 software was used for statistical analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The pooled prevalence of\n                      <jats:italic toggle=\"yes\">K. pneumoniae<\/jats:italic>\n                      was 5%, while the pooled prevalence of ESBL and multidrug resistance (MDR) in\n                      <jats:italic toggle=\"yes\">K. pneumoniae<\/jats:italic>\n                      were 23% and 55%, respectively. Imipenem was the drug of choice (in vitro) against ESBL-KP infection.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Our analyses showed a high prevalence of ESBL-KP and their high resistance toward commonly used drugs. This study highlights the need for the development of new antibiotics for the management of ESBL-KP infections.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11786361221145179","type":"journal-article","created":{"date-parts":[[2023,1,12]],"date-time":"2023-01-12T09:08:08Z","timestamp":1673514488000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Systematic Review and Meta-analysis on Extended-Spectrum \u03b2-lactamases Producing\n                    <i>Klebsiella pneumoniae<\/i>\n                    in Nepal"],"prefix":"10.1177","volume":"16","author":[{"given":"Manita","family":"Shyaula","sequence":"first","affiliation":[{"name":"Central Department of Microbiology, Tribhuvan University, Kathmandu, Bagmati, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Khadka","sequence":"additional","affiliation":[{"name":"Central Department of Microbiology, Tribhuvan University, Kathmandu, Bagmati, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prabin","family":"Dawadi","sequence":"additional","affiliation":[{"name":"Central Department of Microbiology, Tribhuvan University, Kathmandu, Bagmati, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megha Raj","family":"Banjara","sequence":"additional","affiliation":[{"name":"Central Department of Microbiology, Tribhuvan University, Kathmandu, Bagmati, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,1,12]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.5.2197-2200.2003"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2017.27.66.10226"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.14.4.933-951.2001"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.39.6.1211"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.18.4.657-686.2005"},{"key":"e_1_3_3_7_2","article-title":"Overview of ESBL-producing Enterobacteriaceae from a Nordic perspective","volume":"4","author":"Brolund A.","year":"2014","unstructured":"Brolund A. 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