{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T10:35:27Z","timestamp":1784543727049,"version":"3.55.0"},"reference-count":41,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005757","name":"universit\u00e9 cheikh anta diop de dakar","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005757","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbiol\ufffdInsights"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p> The eradication of neonatal Group B Streptococcus (GBS) infections, considered as a major public health priority, necessarily requires a mastery of the data on vaginal carriage in pregnant women. The aims of this study were to determine the prevalence of vaginal carriage of GBS in pregnant women, antibiotic susceptibility, and associated risk factors. This was a cross-sectional, descriptive study conducted over a period of 9\u2009months (July 2020 to March 2021) in pregnant women between 34 and 38\u2009weeks of gestation (WG) followed at the Nabil Choucair health center in Dakar. Identification and antibiotic susceptibility of GBS isolates were performed on the Vitek 2 from vaginal swabs cultured on Granada medium. Demographic and obstetric interview data were collected and analyzed on SPSS (version 25). The level of significance for all statistical tests was set at P\u2009&lt;\u2009.05. The search of GBS vaginal carriage had involved 279 women aged 16 to 46\u2009years, with a median pregnancy age of 34 (34-37) weeks\u2019 gestation. GBS was found in 43 women, for a vaginal carriage rate of 15.4%. In 27.9% (12\/43) of volunteers screened, this carriage was monomicrobial, while in 72.1% (31\/43) of women, GBS was associated with other pathogens such as Candida spp. (60.5%), Trichomonas vaginalis (2.3%), Gardnerella vaginalis (34.9%) and\/or Mobiluncus spp. (11.6%). The level of resistance was 27.9% (12\/43) for penicillin G, 53.5% (23\/43) for erythromycin, 25.6% (11\/43) for clindamycin and 100% for tetracycline. However, the strains had retained fully susceptible to vancomycin and teicoplanin. The main risk factor associated with maternal GBS carriage were ectocervical inflammation associated with contact bleeding (OR\u2009=\u20093.55; P\u2009=\u2009.005). The high rate of maternal vaginal GBS carriage and the levels of resistance to the various antibiotics tested confirm the importance of continuous GBS surveillance in our resource-limited countries. <\/jats:p>","DOI":"10.1177\/11786361231174419","type":"journal-article","created":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T07:02:01Z","timestamp":1685343721000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Vaginal Carriage of Group B <i>Streptococcus<\/i> (GBS) in Pregnant Women, Antibiotic Sensitivity and Associated Risk Factors in Dakar, Senegal"],"prefix":"10.1177","volume":"16","author":[{"given":"Ndeye Safietou","family":"Ngom","sequence":"first","affiliation":[{"name":"Bacteriology-Virology Laboratory, National University Hospital Center Aristide Le Dantec, Dakar, Senegal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Gassama","sequence":"additional","affiliation":[{"name":"Gynecological and Obstetrical Clinic, National University Hospital Center Aristide Le Dantec, Dakar, Senegal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Assane","family":"Dieng","sequence":"additional","affiliation":[{"name":"Bacteriology-Virology Laboratory, National University Hospital Center Aristide Le Dantec, Dakar, Senegal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elhadji Bambo","family":"Diakhaby","sequence":"additional","affiliation":[{"name":"Bacteriology-Virology Laboratory, National University Hospital Center Aristide Le Dantec, Dakar, Senegal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serigne Mbaye Lo","family":"Ndiaye","sequence":"additional","affiliation":[{"name":"Bacteriology-Virology Laboratory, National University Hospital Center Aristide Le Dantec, Dakar, Senegal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alioune","family":"Tine","sequence":"additional","affiliation":[{"name":"Bacteriology-Virology Laboratory, National University Hospital Center Aristide Le Dantec, Dakar, Senegal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farba","family":"Karam","sequence":"additional","affiliation":[{"name":"Bacteriology-Virology Laboratory, National University Hospital Center Aristide Le Dantec, Dakar, Senegal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gora","family":"Lo","sequence":"additional","affiliation":[{"name":"Bacteriology-Virology Laboratory, National University Hospital Center Aristide Le Dantec, Dakar, Senegal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Awa","family":"Ba-Diallo","sequence":"additional","affiliation":[{"name":"Bacteriology-Virology Laboratory, National University Hospital Center Aristide Le Dantec, Dakar, Senegal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheikh Saad Bouh","family":"Boye","sequence":"additional","affiliation":[{"name":"Bacteriology-Virology Laboratory, National University Hospital Center Aristide Le Dantec, Dakar, Senegal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Coumba","family":"Toure-Kane","sequence":"additional","affiliation":[{"name":"Bacteriology-Virology Laboratory, National University Hospital Center Aristide Le Dantec, Dakar, Senegal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdoulaye","family":"Seck","sequence":"additional","affiliation":[{"name":"Laboratory of Medical Biology, Pasteur Institute of Dakar, Senegal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halimatou","family":"Diop-Ndiaye","sequence":"additional","affiliation":[{"name":"Bacteriology-Virology Laboratory, National University Hospital Center Aristide Le Dantec, Dakar, Senegal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makhtar","family":"Camara","sequence":"additional","affiliation":[{"name":"Bacteriology-Virology Laboratory, National University Hospital Center Aristide Le Dantec, Dakar, Senegal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,5,29]]},"reference":[{"key":"bibr1-11786361231174419","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix653"},{"key":"bibr2-11786361231174419","doi-asserted-by":"publisher","DOI":"10.1038\/nmicrobiol.2016.67"},{"key":"bibr3-11786361231174419","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(16)30055-X"},{"key":"bibr4-11786361231174419","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.1.83-89.2004"},{"key":"bibr5-11786361231174419","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2016.201"},{"key":"bibr6-11786361231174419","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix660"},{"key":"bibr7-11786361231174419","doi-asserted-by":"publisher","DOI":"10.1159\/000265942"},{"key":"bibr8-11786361231174419","unstructured":"Centers for Disease Control and Prevention. 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