{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T21:27:56Z","timestamp":1789421276325,"version":"build-2803163510"},"reference-count":40,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Nutr Metab Insights"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Vitamin D deficiency is common among children and adolescents and can be affected by several factors such as puberty and obesity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The aim of this study was to evaluate vitamin D status in children and adolescents and to analyse the influence of puberty and obesity on its level.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>A cross-sectional study was carried-out, in which clinical and biochemical data were gathered from 384 healthy children and adolescents between May 2019 to May 2020.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>220 females and 164 males were enrolled (aged 7-16 years; mean \u00b1 SD: 11 \u00b1 2.5). Vitamin D deficiency was found in 49% of the total cases and was significantly more prevalent in females than males (33.1% in female; 15.9% in male, P &lt; .001). Mean vitamin D level was lower in obese children compared with non-obese ( P &lt; .001). Non-obese group had significantly higher levels of vitamin D in Tanner stage IV of puberty than obese individuals (20.1 \u00b1 17.0 vs 5.4 \u00b1 2.0) ( P = .03). Vitamin D levels were significantly lower in females than males only in Tanner stage II (12.3 \u00b1 9.0 vs 19.6 \u00b1 16.6) ( P = .005). The lowest level of Vitamin D was in Tanner stage \u2163-\u2164 in boys and in Tanner stage \u2161-\u2162 in girls ( P &lt; .001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Puberty is an additional risk factor for vitamin D deficiency especially in girls and obese children. This increased risk, together with the fact that most important time for building a proper skeleton is during childhood and adolescent, makes it essential to monitor vitamin D in these age groups.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11786388211018726","type":"journal-article","created":{"date-parts":[[2021,5,29]],"date-time":"2021-05-29T15:50:35Z","timestamp":1622303435000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":27,"title":["Vitamin D Deficiency in Children and Adolescents: Role of Puberty and Obesity on Vitamin D Status"],"prefix":"10.1177","volume":"14","author":[{"given":"Hedyeh","family":"Saneifard","sequence":"first","affiliation":[{"name":"Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjan","family":"Shakiba","sequence":"additional","affiliation":[{"name":"Mofid Children 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