{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T17:56:09Z","timestamp":1784829369720,"version":"3.55.0"},"reference-count":115,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010731","name":"faculty of medicine, chiang mai university","doi-asserted-by":"publisher","award":["Grant for the Institutional scientific project, IP"],"award-info":[{"award-number":["Grant for the Institutional scientific project, IP"]}],"id":[{"id":"10.13039\/501100010731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Med Insights Cardiol"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>Visceral adipose tissue is an independent risk factor for the development of atherosclerotic coronary disease, arterial hypertension, diabetes and metabolic syndrome. Right heart morphology often involves the presence of adipose tissue, which can be quantified by non-invasive imaging methods. The last decade brought a wealth of new insights into the function and morphology of adipose tissue, with great emphasis on its role in the pathogenesis of heart disease. Cardiac adipose tissue is involved in thermogenesis, mechanical protection of the heart and energy storage. However, it can also be an endocrine organ that synthesises numerous pro-inflammatory and anti-inflammatory cytokines, the effect of which is accomplished by paracrine and vasocrine mechanisms. Visceral adipose tissue has several compartments that differ in their embryological origin and vascularisation. Deficiency of cardiac adipose tissue, often due to chronic pathological conditions such as oncological diseases or chronic infectious diseases, predicts increased mortality and morbidity. To date, knowledge about the influence of visceral adipose tissue on cardiac morphology is limited, especially the effect on the morphology of the right heart in a state of excess or deficient visceral adipose tissue.<\/jats:p>","DOI":"10.1177\/11795468211041330","type":"journal-article","created":{"date-parts":[[2021,9,29]],"date-time":"2021-09-29T05:19:10Z","timestamp":1632892750000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Right Heart Morphology and Its Association With Excessive and Deficient Cardiac Visceral Adipose Tissue"],"prefix":"10.1177","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3169-3658","authenticated-orcid":false,"given":"Domagoj","family":"Vu\u010di\u0107","sequence":"first","affiliation":[{"name":"Department for Internal Medicine, Division of Cardiology, General Hospital Doctor Josip Ben\u010devi\u0107, Slavonski Brod, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4136-820X","authenticated-orcid":false,"given":"Nikola","family":"Bijeli\u0107","sequence":"additional","affiliation":[{"name":"Department for Histology and Embriology, Faculty of Medicine, University Josip Juraj Strossmayer in Osijek, Osijek, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edi","family":"Ro\u0111ak","sequence":"additional","affiliation":[{"name":"Department for Histology and Embriology, Faculty of Medicine, University Josip Juraj Strossmayer in Osijek, Osijek, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasmina","family":"Rajc","sequence":"additional","affiliation":[{"name":"Department for Pathology and Forensic Medicine, University Hospital Center Osijek, Osijek, Croatia"},{"name":"Department for Pathology, Faculty of Medicine, University Josip Juraj Strossmayer in Osijek, Osijek, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boris","family":"Dumen\u010di\u0107","sequence":"additional","affiliation":[{"name":"Department for Pathology and Forensic Medicine, University Hospital Center Osijek, Osijek, Croatia"},{"name":"Department for Pathology, Faculty of Medicine, University Josip Juraj Strossmayer in Osijek, Osijek, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatjana","family":"Belovari","sequence":"additional","affiliation":[{"name":"Department for Histology and Embriology, Faculty of Medicine, University Josip Juraj Strossmayer in Osijek, Osijek, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damir","family":"Mihi\u0107","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine, University Center Hospital Osijek, Osijek, Croatia"},{"name":"Department for Internal Medicine, Faculty of Medicine, University Josip Juraj Strossmayer in Osijek, Osijek, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9890-6489","authenticated-orcid":false,"given":"Kristina","family":"Selthofer-Relati\u0107","sequence":"additional","affiliation":[{"name":"Department for Internal Medicine, Faculty of Medicine, University Josip Juraj Strossmayer in Osijek, Osijek, Croatia"},{"name":"Department for Heart and Vascular Diseases, University Center Hospital Osijek, Osijek, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,9,29]]},"reference":[{"key":"bibr1-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1097\/HPC.0b013e318057d4c9"},{"key":"bibr2-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.106.131755"},{"key":"bibr3-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2008.10.015"},{"key":"bibr4-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000099542.57313.C5"},{"key":"bibr5-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2840-5-1"},{"key":"bibr6-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2007.03.019"},{"key":"bibr7-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1007\/s40618-015-0258-y"},{"key":"bibr8-11795468211041330","doi-asserted-by":"publisher","DOI":"10.2337\/dc11-s250"},{"key":"bibr9-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2015.08.016"},{"key":"bibr10-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2011.09.006"},{"key":"bibr11-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1007\/s12410-010-9012-1"},{"key":"bibr12-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1097\/01.rti.0000213576.39774.68"},{"key":"bibr13-11795468211041330","doi-asserted-by":"publisher","DOI":"10.20471\/acc.2018.57.01.15"},{"key":"bibr14-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.jjcc.2014.03.015"},{"key":"bibr15-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.1283"},{"key":"bibr16-11795468211041330","first-page":"1294","volume":"38","author":"Wong CX","year":"2017","journal-title":"Eur Heart J"},{"key":"bibr17-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.821181"},{"key":"bibr18-11795468211041330","doi-asserted-by":"publisher","DOI":"10.2337\/dc10-2083"},{"key":"bibr19-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2008.11.003"},{"key":"bibr20-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2010.05.005"},{"key":"bibr21-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1038\/ncpcardio0319"},{"key":"bibr22-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12242"},{"key":"bibr23-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M500294-JLR200"},{"key":"bibr24-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000183883.72263.13"},{"key":"bibr25-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1038\/nri2921"},{"key":"bibr26-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.carpath.2004.08.005"},{"key":"bibr27-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.1.1.93"},{"key":"bibr28-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1996.tb14264.x"},{"key":"bibr29-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2013.05.036"},{"key":"bibr30-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/0022-4804(87)90148-X"},{"key":"bibr31-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0020424"},{"key":"bibr32-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-3145"},{"key":"bibr33-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2008.06.013"},{"key":"bibr34-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1007\/s40279-018-0903-7"},{"key":"bibr35-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/9854085"},{"key":"bibr36-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.679779"},{"key":"bibr37-11795468211041330","first-page":"74","volume":"108","author":"Okoshi MP","year":"2017","journal-title":"Arq Bras Cardiol"},{"key":"bibr38-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01448-6"},{"key":"bibr39-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)01102-5"},{"key":"bibr40-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.06.046"},{"key":"bibr41-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2003.05.050"},{"key":"bibr42-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/365404"},{"key":"bibr43-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2003.45"},{"key":"bibr44-11795468211041330","doi-asserted-by":"publisher","DOI":"10.4103\/1995-705X.76801"},{"key":"bibr45-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1253\/circj.71.536"},{"key":"bibr46-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2007.118471"},{"key":"bibr47-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2010.11.008"},{"key":"bibr48-11795468211041330","first-page":"e18","volume":"101","author":"Bertaso AG","year":"2013","journal-title":"Arq Bras Cardiol"},{"key":"bibr49-11795468211041330","doi-asserted-by":"publisher","DOI":"10.17219\/acem\/104526"},{"key":"bibr50-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2009.07.032"},{"key":"bibr51-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0074926"},{"key":"bibr52-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2008.6"},{"key":"bibr53-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2011.08.067"},{"key":"bibr54-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2008.05.002"},{"key":"bibr55-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.ihj.2015.08.005"},{"key":"bibr56-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-030698"},{"key":"bibr57-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2008.04.058"},{"key":"bibr58-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2008.08.010"},{"key":"bibr59-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20150773"},{"key":"bibr60-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.114.000788"},{"key":"bibr61-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1177\/2047487317689976"},{"key":"bibr62-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2008.04.002"},{"key":"bibr63-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.828970"},{"key":"bibr64-11795468211041330","volume":"98","author":"Kim HJ","year":"2019","journal-title":"Medicine"},{"key":"bibr65-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2011.10.014"},{"key":"bibr66-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.12.051"},{"key":"bibr67-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000004164"},{"key":"bibr68-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.113.000582"},{"key":"bibr69-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2012.11.021"},{"key":"bibr70-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2005.02054.x"},{"key":"bibr71-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1097\/01.rct.0000236416.05267.6c"},{"key":"bibr72-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2006.07.174"},{"key":"bibr73-11795468211041330","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.2011.3906"},{"key":"bibr74-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20190770"},{"key":"bibr75-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2011.117"},{"key":"bibr76-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1002\/cphy.c160034"},{"key":"bibr77-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.06.016"},{"key":"bibr78-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0157654"},{"key":"bibr79-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-0172"},{"key":"bibr80-11795468211041330","volume-title":"Cardiovascular Pathology","author":"Buja LM","year":"2016","edition":"4"},{"key":"bibr81-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.54.4.321"},{"key":"bibr82-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.10372"},{"key":"bibr83-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-0436"},{"key":"bibr84-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.carpath.2010.07.005"},{"key":"bibr85-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1681.2011.05601.x"},{"key":"bibr86-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvr212"},{"key":"bibr87-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M800147-JLR200"},{"key":"bibr88-11795468211041330","doi-asserted-by":"publisher","DOI":"10.2174\/138161209787582101"},{"key":"bibr89-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1096\/fj.04-2263com"},{"key":"bibr90-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-36914-y"},{"key":"bibr91-11795468211041330","doi-asserted-by":"publisher","DOI":"10.3390\/cells9020451"},{"key":"bibr92-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.116.004998"},{"key":"bibr93-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-015-1327-x"},{"key":"bibr94-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60256-7"},{"key":"bibr95-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/5610347"},{"key":"bibr96-11795468211041330","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.09.3450"},{"key":"bibr97-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00332-X"},{"key":"bibr98-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2013.08.032"},{"key":"bibr99-11795468211041330","doi-asserted-by":"publisher","DOI":"10.5603\/CJ.a2018.0123"},{"key":"bibr100-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm342"},{"key":"bibr101-11795468211041330","first-page":"269","volume":"53","author":"Radu RI","year":"2012","journal-title":"Rom J Morphol Embryol"},{"key":"bibr102-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2013.04.010"},{"key":"bibr103-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.002238"},{"key":"bibr104-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2532082290"},{"key":"bibr105-11795468211041330","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.08.1608"},{"key":"bibr106-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-200407000-00004"},{"key":"bibr107-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/S1054-8807(03)00134-0"},{"key":"bibr108-11795468211041330","first-page":"65","volume":"13","author":"Baroldi G","year":"1997","journal-title":"Can J Cardiol"},{"key":"bibr109-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1136\/heart.88.6.665"},{"key":"bibr110-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(96)00163-0"},{"key":"bibr111-11795468211041330","volume-title":"Management","author":"Dumitrescu SI","year":"2018","edition":"1"},{"key":"bibr112-11795468211041330","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2009.10.2.164"},{"key":"bibr113-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.10488"},{"key":"bibr114-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2004.045930"},{"key":"bibr115-11795468211041330","doi-asserted-by":"publisher","DOI":"10.1378\/chest.124.6.2068"}],"container-title":["Clinical Medicine Insights: Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11795468211041330","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/11795468211041330","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11795468211041330","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:13:44Z","timestamp":1777389224000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/11795468211041330"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":115,"alternative-id":["10.1177\/11795468211041330"],"URL":"https:\/\/doi.org\/10.1177\/11795468211041330","relation":{},"ISSN":["1179-5468","1179-5468"],"issn-type":[{"value":"1179-5468","type":"print"},{"value":"1179-5468","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1]]},"article-number":"11795468211041330"}}