{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:01:45Z","timestamp":1777500105272,"version":"3.51.4"},"reference-count":47,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Med Insights Cardiol"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>We aimed to investigate the incidence of new acute myocardial infarction (AMI), in patients with Coronavirus disease (COVID-19) who had old MI. We hypothesized that COVID-19 increases the rate of repeated AMI in this population regardless of age and gender.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective analysis was conducted for adult patients admitted with COVID-19 and developed thromboembolic event (TEE) in 2020. Patients were categorized based on the history of old MI, new MI, age, and gender.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Among 16,903 patients with COVID-19 who were admitted, 210 (1.2%) developed TEE (89% were males, 55% were &lt;55\u2009years old, and 80.5% had an old MI). COVID-19 was severe in 32% of cases. AMI occurred in 160 patients (42.5% STEMI and 57.5% NSTEMI). In patients with prior MI, 92.5% developed another AMI. NSTEMI was higher in patients with severe COVID-19 than STEMI (33% vs 21%). Patients with severe COVID-19 had higher mortality (39.4% vs 5.6%), fewer rates of prior MI (74% vs 83%), hypertension (40% vs 60%), and STEMI (31.8% vs 46.5%) than mild COVID-19 patients. On multivariable analysis, COVID-19 severity was an independent predictor of mortality (OR10; 95%CI 1.62-67.19) after adjustment for age, gender, diabetes mellitus, C-reactive protein, serum Ferritin, Procalcitonin, and Fibrinogen values, and prior or new MI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Patients with old MI could develop a new AMI in 80% of COVID-19. However, the mortality was higher in patients without a history of MI due to the severity of COVID-19. Attention should be given to patients who possess thrombotic risk factors in pandemics.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11795468241301133","type":"journal-article","created":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T06:49:38Z","timestamp":1734504578000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["COVID-19 Increases the Risk of New Myocardial Infarction in Patients with Old Myocardial Infarction: A Retrospective Observational Study"],"prefix":"10.1177","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2584-953X","authenticated-orcid":false,"given":"Ayman","family":"El-Menyar","sequence":"first","affiliation":[{"name":"Clinical Research, Trauma and Vascular Surgery, Hamad Medical Corporation, Doha, Qatar"},{"name":"Clinical Medicine, Weill Cornell Medical College, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed Faidh","family":"Ramzee","sequence":"additional","affiliation":[{"name":"Trauma Surgery Section, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Asim","sequence":"additional","affiliation":[{"name":"Clinical Research, Trauma and Vascular Surgery, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fakhar","family":"Shahid","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaser M","family":"Ata","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamzah","family":"El Baba","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Areen","family":"Fino","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arun P","family":"Nair","sequence":"additional","affiliation":[{"name":"Communicable Disease Center (CDC), Hamad Medical Corporation, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruben","family":"Peralta","sequence":"additional","affiliation":[{"name":"Trauma Surgery Section, Hamad Medical Corporation, Doha, Qatar"},{"name":"Department of Surgery, Universidad Nacional Pedro Henriquez Urena, Santo Domingo, Dominican Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muna A","family":"Almaslamani","sequence":"additional","affiliation":[{"name":"Communicable Disease Center (CDC), Hamad Medical Corporation, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5299-9106","authenticated-orcid":false,"given":"Jassim","family":"Al Suwaidi","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Heart Hospital, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan","family":"Al-Thani","sequence":"additional","affiliation":[{"name":"Trauma Surgery Section, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandro","family":"Rizoli","sequence":"additional","affiliation":[{"name":"Trauma Surgery Section, Hamad Medical Corporation, Doha, 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